ISSN:
1420-9071
Keywords:
Cannabinoids
;
stereospecificity
;
psychotropic activity
;
drug discrimination
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The 1,1-dimethylheptyl homolog of (−)-(3R,4R)-7-hydroxy-delta-6-tetrahydrocannabinol (compoundII) is highly psychotropic in mice, rats and pigeons. The (+)-(3S,4S) enantiomer (III) was found to be psychotropically inactive at doses up to several thousand times those of the ED50 of (II).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01959156
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