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  • 1
    Publication Date: 2015-08-06
    Description: Author(s): S. Eliseev, K. Blaum, M. Block, S. Chenmarev, H. Dorrer, Ch. E. Düllmann, C. Enss, P. E. Filianin, L. Gastaldo, M. Goncharov, U. Köster, F. Lautenschläger, Yu. N. Novikov, A. Rischka, R. X. Schüssler, L. Schweikhard, and A. Türler The atomic mass difference of Ho 163 and Dy 163 has been directly measured with the Penning-trap mass spectrometer SHIPTRAP applying the novel phase-imaging ion-cyclotron-resonance technique. Our measurement has solved the long-standing problem of large discrepancies in the Q value of the electron cap… [Phys. Rev. Lett. 115, 062501] Published Wed Aug 05, 2015
    Keywords: Nuclear Physics
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 2
    Publication Date: 2016-03-26
    Description: In eukaryotic cells, the nuclear envelope separates the genomic DNA from the cytoplasmic space and regulates protein trafficking between the two compartments. This barrier is only transiently dissolved during mitosis. Here, we found that it also opened at high frequency in migrating mammalian cells during interphase, which allowed nuclear proteins to leak out and cytoplasmic proteins to leak in. This transient opening was caused by nuclear deformation and was rapidly repaired in an ESCRT (endosomal sorting complexes required for transport)-dependent manner. DNA double-strand breaks coincided with nuclear envelope opening events. As a consequence, survival of cells migrating through confining environments depended on efficient nuclear envelope and DNA repair machineries. Nuclear envelope opening in migrating leukocytes could have potentially important consequences for normal and pathological immune responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Raab, M -- Gentili, M -- de Belly, H -- Thiam, H R -- Vargas, P -- Jimenez, A J -- Lautenschlaeger, F -- Voituriez, Raphael -- Lennon-Dumenil, A M -- Manel, N -- Piel, M -- New York, N.Y. -- Science. 2016 Apr 15;352(6283):359-62. doi: 10.1126/science.aad7611. Epub 2016 Mar 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France. Institut Pierre-Gilles de Gennes, PSL Research University, F-75005 Paris, France. ; Institut Curie, PSL Research University, INSERM, U 932, F-75005 Paris, France. ; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France. ; Laboratoire de Physique Theorique de la Matiere Condensee, CNRS UMR 7600, Universite Pierre et Marie Curie, Paris, France. Laboratoire Jean Perrin, CNRS UMR 8237, Universite Pierre et Marie Curie, Paris, France. ; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France. Institut Pierre-Gilles de Gennes, PSL Research University, F-75005 Paris, France. matthieu.piel@curie.fr.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/27013426" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Death ; *Cell Movement ; Cytoplasm/metabolism ; *DNA Breaks, Double-Stranded ; DNA Repair ; Endosomal Sorting Complexes Required for Transport/genetics/*metabolism ; HeLa Cells ; Humans ; Immunity/genetics ; Interphase ; Leukocytes/immunology/ultrastructure ; Mice ; Nuclear Envelope/*ultrastructure ; Nuclear Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 31 (1966), S. 1679-1682 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 33 (1968), S. 2620-2627 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 33 (1968), S. 2627-2633 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 33 (1968), S. 4316-4316 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 252 (1974), S. 179-179 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 54 (1915), S. 352-352 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Brookfield, Conn. : Wiley-Blackwell
    Polymer Composites 5 (1984), S. 339-346 
    ISSN: 0272-8397
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Properties are identified which pass through a maximum when the filler loading in a polymer is increased; all are failure properties. Under standard test conditions of strain rate and temperature, the order of the failure property maxima with increasing filler loadings is identical in different polymers. The optimum level for maximum tear strength is higher than the optimum level for tensile strength. In general, the optimum level is even higher for abrasion resistance. The order in which these maxima develop is different when the degree of crosslinking is increased. The optimum level depends on characteristics of the polymer, e.g., the glass transition temperature. It can be shown that an increase in the pore volume of silica fillers, or an increase in the length of the crystalline segment in thermoplastic elastomers, leads to similar property trends as increased filler levels. Thus, the property trend which was established for increasing filler levels provides a scheme against which polymer or compound modifications can be assessed. The implications of the observed property trends on several generalizations in the literature are assessed.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 24 (1979), S. 605-634 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: An attempt is made to distinguish properties of elastomers by types. “Basic properties of materials” or “network properties” in elastomers are properties which either increase or decrease from the liquid to the solid state of materials or over the range of the “elastomeric plateau” of elastomers. From these are distinguished properties that exhibit characteristic maxima and are therefore “maximum properties” or bivalued properties. Mechanical failure properties show the characteristics of “maximum properties.” The maxima in “maximum properties” generally do not coincide. This noncoincidence of the maxima with a change in a “basic property of a material” has major theoretical and practical implications, for example, it is the cause of the crossovers in the relative performance rating of materials under different test conditions. The implications of this noncoincidence of the failure property maxima on the relevance of correlations between these properties are discussed. A change in the testing conditions is reflected in a shift of the optimum value in a “basic property of a material” with respect to a specific “maximum property.” Data and certain conclusions in the literature are interpreted on the basis of this concept. Examples of the limitations of the validity of mathematical relationships are presented. Also, a definition of the term “state of cure” is proposed and a suggestion for the rating of severities of test equipment and applications of elastomeric materials recommended. The effect of increased degrees of crosslinking for a series of polymers and crosslinking agents is assessed. It is suggested that the “mechanisms” of failure properties will remain elusive if their rationalization is attempted on the basis of other failure properties, e.g., the mechanism of abrasion on that of tear strength or cut growth. The main purpose of this proposal is to provide support for a drastic reduction in laboratory testing by identifying those properties which can lead to different relative ratings in routine evaluations and actual applications. A more empirical approach to materials evaluations is recommended based on the calibration of laboratory instrumentation with respect to specific applications. A de-emphasis of routine evaluations of materials on the basis of their “maximum properties” seems to be justified.
    Additional Material: 22 Ill.
    Type of Medium: Electronic Resource
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