ISSN:
0030-4921
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The NMR spectra of a series of chiral propionamides have been determined in D(+)1-phenylethylamine solution. The α-methine protons of the propionic acid moiety in the propionamide enantiomers were found to be anisochronous in this solvent. The sense of non-equivalence of these protons was found to be the same for all members of a homochiral series. The chemical shift difference between their signals was demonstrated to be dependent upon the temperature and concentration of the solution. A method is described whereby the enantiomeric purity of the amides could be calculated from these signals in cases where the position of the baseline in their spectra was unknown.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1270050905
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