ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The aim of this study is to analyse the influence of differently fabricated HA-scaffolds onbone marrow stromal cells. Therefore, three methods were used (a polyurethane (PU)-replicatechnique, the dispense-plotting and a negative mould technique) to produce porous hydroxyapatite(HA) ceramics. The different HA-scaffolds were then cultivated with an osteoblastic precursor cellline. In our study, highest cell proliferation and differentiation was achieved by using (PU)-replicatechnique. However, this study shows also that all three types of scaffolds are suitable for tissueengineering applications and as bone substitute material. The knowledge about the influence of poresize and geometry on the cell behaviour will help to tailor scaffolds, by different 3D fabricationmethods, for the needs of tissue engineering laboratories or patients
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.1181.pdf
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