Publication Date:
1981-05-01
Description:
Discrete voltage fluctuations that occur spontaneously or in response to dim lights can be recorded from the ventral photoreceptors of Limulus. The injection of vanadate or the hydrolysis-resistant analog of guanosine triphosphate, GTP-gamma-S, into ventral photoreceptors induces the production of discrete waves in the dark. The chemically induced discrete waves are similar to those induced by light. Ventral photoreceptors may contain a guanyl nucleotide binding protein whose activation by vanadate or GTP-gamma-S induces the discrete waves.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fein, A -- Corson, D W -- New York, N.Y. -- Science. 1981 May 1;212(4494):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6782676" target="_blank"〉PubMed〈/a〉
Keywords:
Action Potentials/drug effects
;
Adenylyl Cyclases/metabolism/physiology
;
Animals
;
Carrier Proteins/physiology
;
Enzyme Activation/drug effects
;
Fluorides/pharmacology
;
GTP-Binding Proteins
;
Guanosine 5'-O-(3-Thiotriphosphate)
;
Guanosine Triphosphate/*analogs & derivatives/pharmacology/physiology
;
Horseshoe Crabs/*physiology
;
Photoreceptor Cells/*drug effects
;
Thionucleotides/*pharmacology
;
Vanadates
;
Vanadium/*pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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