Publication Date:
2004-06-26
Description:
The ability of rats to use their whiskers for fine tactile discrimination rivals that of humans using their fingertips. Rats perform discriminations rapidly and accurately while palpating the environment with their whiskers. This suggests that whisker deflections produce a robust and reliable neural code. Whisker primary afferents respond with highly reproducible temporal spike patterns to transient stimuli. Here we show that, with the use of a linear kernel, any of these reproducible response trains recorded from an individual neuron can reliably predict complex whisker deflections. These predictions are significantly improved by integrating responses from neurons with opposite angular preferences.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557422/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557422/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jones, Lauren M -- Depireux, Didier A -- Simons, Daniel J -- Keller, Asaf -- F31 NS046100/NS/NINDS NIH HHS/ -- F31 NS46100-01/NS/NINDS NIH HHS/ -- NS19950/NS/NINDS NIH HHS/ -- R01 DC-05937-01/DC/NIDCD NIH HHS/ -- R01 DC005937/DC/NIDCD NIH HHS/ -- R01 NS019950/NS/NINDS NIH HHS/ -- R01 NS031078/NS/NINDS NIH HHS/ -- R01 NS31078/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 2004 Jun 25;304(5679):1986-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Program in Neuroscience and Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15218153" target="_blank"〉PubMed〈/a〉
Keywords:
Acoustic Stimulation
;
Action Potentials
;
Afferent Pathways
;
Analysis of Variance
;
Animals
;
Female
;
Neurons/*physiology
;
Rats
;
Touch
;
Trigeminal Ganglion/cytology/*physiology
;
Vibrissae/*innervation/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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