Publication Date:
2019-01-04
Description:
Climate change, changing farming practices, social and demographic changes and rising levels of antibiotic resistance are likely to lead to future increases in opportunistic bacterial infections that are more difficult to treat. Uncovering the prevalence and identity of pathogenic bacteria in the environment is key to assessing transmission risks. We describe the first use of the Wax moth larvaGalleria mellonella, a well-established model for the mammalian innate immune system, to selectively enrich and characterize pathogens from coastal environments in the South West of the UK. Whole-genome sequencing of highly virulent isolates revealed amongst others aProteus mirabilisstrain carrying theSalmonellaSGI1 genomic island not reported from the UK before and the recently described speciesVibrio injenensishitherto only reported from human patients in Korea. Our novel method has the power to detect bacterial pathogens in the environment that potentially pose a serious risk to public health.
Electronic ISSN:
2167-8359
Topics:
Biology
,
Medicine
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