ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] When nuclei are isolated by conventional procedures, their DNA is invariably broken, mainly by endonucleolytic nicking8. However, if living cells are lysed in a detergent, 2 M salt and chelating agents, structures are released which resemble nuclei4'9"12. Such nucleoids contain naked histone-free ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/292552a0
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