Publication Date:
2013-06-19
Description:
Article The Parkinson’s disease-associated protein Parkin regulates the fate of damaged mitochondria by ubiquitinating mitochondrial substrates. Riley et al . present the crystal structure of the Parkin-R0RBR domain, providing new insight into the catalytic mechanism of the enzyme. Nature Communications doi: 10.1038/ncomms2982 Authors: B.E. Riley, J.C. Lougheed, K. Callaway, M. Velasquez, E. Brecht, L. Nguyen, T. Shaler, D. Walker, Y. Yang, K. Regnstrom, L. Diep, Z. Zhang, S. Chiou, M. Bova, D.R. Artis, N. Yao, J. Baker, T. Yednock, J.A. Johnston
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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