ISSN:
1573-8221
Keywords:
prednisolone
;
cortisol
;
pharmacokinetics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Individual characteristics of prednisolone and cortisol pharmacokinetics in five young healthy subjects administered prednisolone in a single oral dose of 25 mg are described. The results suggests that prednisolone inhibits the glucocorticoid function of the adrenal cortex. It is concluded that the pharmacokinetics of prednisolone can be assessed from the reductions in serum cortisol concentration which it causes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446026
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