Publication Date:
2015-04-09
Description:
Key Points C3 mutations in aHUS commonly result in impaired complement regulation, C3 consumption, and a poor renal outcome. C3 mutations tend to cluster at the protein surface and facilitate mapping of putative binding sites for the regulatory proteins.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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