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  • 1
    Electronic Resource
    Electronic Resource
    Ion exposure chambers for small animals (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 7 (1986), S. 1-11 
    Details
    ISSN: 0197-8462
    Keywords: ion exposure chamber ; ion concentration ; current density ; electric field ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Ion exposure chambers that have been designed and tested for use in biological and behavioral research with small animals are described in this report. The chambers exhibit an acceptable degree of uniformity in ion concentration, current density, and electric field within the exposure area. Gaseous by-products of corona discharge (O3 and NO2) have been measured and found to be 〈 .01 ppm and 〈 .1 ppm, respectively. Filtered air is fed to the individual exposure chambers, and temperature and humidity are well controlled. Noise due to corona and the air delivery system has been measured.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250070102
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Behavioral monitoring of rats during exposure to air ions and DC electric fields (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 7 (1986), S. 329-339 
    Details
    ISSN: 0197-8462
    Keywords: air ions ; DC electric fields ; locomotor activity ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Air ions and direct current (DC) electric fields have been reported to exert subtle behavioral and biological effects on rodents and humans. These effects often appear inconsistent, yet there have been few attempts to resolve these inconsistencies by experimental replication. Rats exposed to negatively or positively charged air ions over a wide range of concentrations and exposure periods have been reported to show alterations in their level of locomotor activity. In this study, locomotor activity of Sprague-Dawley rats was quantified during exposure to either (1) unipolar air ions and DC fields of the same polarity or (2) DC fields alone. Both polarities were studied. Air ion concentrations were 5.0 × 103, DC fields were 3 kV/m, and exposures lasted 2, 18, or 66 h. In one experiment rats were exposed to DC fields of 12 kV/m. No exposure condition exerted any effect on locomotor activity or rearing behavior. In addition, no behavioral perturbations were observed after the onset of any of the exposure conditions, suggesting that the rats may have failed to detect the altered environment.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250070309
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  • 3
    Electronic Resource
    Electronic Resource
    Inhalation chambers for air ion research (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 4 (1983), S. 167-180 
    Details
    ISSN: 0197-8462
    Keywords: air ions ; corona discharge inhalation system ; DC electric fields ; small animal exposure system ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Many previous problems in establishing the nature of biological and behavioral effects of small air ions have been due to poor control over the ion-inhalation microclimate, resulting in nonuniform electrical fields and highly uneven concentrations of small air ions. We have developed a corona discharge air ion-inhalation system for use with animals that incorporates rigorous control over the microclimate and produces highly uniform concentrations of small air ions throughout the exposure area.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250040207
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  • 4
    Electronic Resource
    Electronic Resource
    Acute exposure of rats to air ions: Effects on the regional concentration and utilization of serotonin in brain (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 8 (1987), S. 173-181 
    Details
    ISSN: 0197-8462
    Keywords: DC electric fields ; 5-hydroxyindoleacetic acid ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Exposure to electrically charged gas molecules (air ions) has been reported to influence physiological and behavioral functions in animals and humans although there is controversy as to whether these findings are valid. A popular hypothesis concerning the reported effects of air ions is that alterations in serotonin (5HT) metabolism, particularly in the brain, are involved. We measured the concentration and turnover of 5HT in rats exposed to 5.0 × 105 ions/cm3 for up to 66 hours. Contrary to previous reports of other investigators, we were unable to demonstrate any effect of exposure to air ions or associated DC electric fields on the concentration or turnover of 5HT in rats under carefully controlled and characterized exposure conditions.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250080208
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  • 5
    Electronic Resource
    Electronic Resource
    Regional turnover of norepinephrine and dopamine in rat brain following acute exposure to air ions (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 6 (1985), S. 415-425 
    Details
    ISSN: 0197-8462
    Keywords: air ions ; DC electric fields ; brain catecholamines ; dopamine ; norepinephrine ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Exposure to air ions has been reported to influence serotonin (5HT), although critical reviews of these studies and previous measurements in our laboratory of the concentration, release, and utilization of brain 5HT indicate that neither the data nor the interpretations of the data are particularly convincing. Measurements of other possibly relevant neuro-transmitter systems - norepinephrine (NE) and dopamine (DA) - were made in brain regions selected because of their importance in the modulation of brain functions relating to motivation, arousal, endocrine function, and motor activity, all responses that have been reported to be influenced by air ion exposure. Results indicate that exposure of male Holtzman rats to high concentrations (5.0 × 105/cm3) of positive or negative air ions or to DC electric fields (3.0 kV/m) for periods up to 66 h failed to affect the concentration of NE or DA significantly in any of the brain regions.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250060408
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  • 6
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    Biological effects of small air ions: A review of findings and methods (1984)
    Elsevier
    Details
    Publication Date: 1984-08-01
    Print ISSN: 0013-9351
    Electronic ISSN: 1096-0953
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by Elsevier
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