ISSN:
1573-3904
Keywords:
Cellular uptake
;
Vector peptide
;
Conformation
;
Circular dichroism
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract We describe the synthesis of an amphipathic vectorpeptide which is able to form complexes with nucleicacids. Based on circular dichroism investigations, the nature of thestructure obtained in water is questioned. Thepeptide adopts an α-helical structure in TFEand is partially in a β-sheet conformation inphosphate buffer at low peptide concentrations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008899427075
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