ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] According to Knudson's hypothesis9, both alleles of a suppressor gene are independently inactivated, generally by point mutation of one allele and deletion of the other wild-type allele. Point mutation of p16 has been described in melanoma kindreds, pancreatic, and some esophageal and lung ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/ng1095-210
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