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  • 1
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    In:  Tectonophysics, Warszawa, Conseil de l'Europe, vol. 361, no. 1-2, pp. 61-82, pp. L19608, (ISBN: 0-12-018847-3)
    Publication Date: 2003
    Keywords: Structural geology ; Geol. aspects ; Tectonics ; China
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  • 2
    Publication Date: 2015-08-11
    Description: Author(s): Su-Yang Xu, Chang Liu, I. Belopolski, S. K. Kushwaha, R. Sankar, J. W. Krizan, T.-R. Chang, C. M. Polley, J. Adell, T. Balasubramanian, K. Miyamoto, N. Alidoust, Guang Bian, M. Neupane, H.-T. Jeng, C.-Y. Huang, W.-F. Tsai, T. Okuda, A. Bansil, F. C. Chou, R. J. Cava, H. Lin, and M. Z. Hasan A three-dimensional (3D) Dirac semimetal is a novel state of quantum matter which has recently attracted much attention as an apparent 3D version of graphene. In this paper, we report results on the electronic structure of the 3D Dirac semimetal Na 3 Bi at a surface that reveals its nontrivial ground … [Phys. Rev. B 92, 075115] Published Mon Aug 10, 2015
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 3
    Publication Date: 2016-08-09
    Description: Galectin-12 is a member of an animal lectin family with affinity for β-galactosides and containing consensus amino acid sequences. Here, we found that galectin-12 was expressed in macrophages and thus aimed to determine how galectin-12 affects inflammation and macrophage polarization and activation. The ablation of galectin-12 did not affect bone marrow cells to differentiate into macrophages, but reduced phagocytic activity against Escherichia coli and lowered the secretion of nitric oxide. The ablation of galectin-12 also resulted in the polarization of macrophages into the M2 direction, as indicated by increases in the levels of M2 markers, namely, resistin-like β (FIZZ1) and chitinase 3-like 3 (Ym1), as well as a reduction in the expression levels of a number of M1 pro-inflammatory cytokines. We found that the diminished expression of pro-inflammatory cytokines in macrophages resulting from galectin-12 deletion was due to reduced activation of IKKα/β, Akt and ERK, which in turn caused decreased activation of NF-B and activator protein 1. The activation of STAT3 was much higher in Gal12 –/– macrophages activated by lipopolysaccharide, which was correlated with higher levels of IL-10. Adipocytes showed higher insulin sensitivity when treated with Gal12 –/– macrophage-conditioned media than those treated with Gal12 +/+ macrophages. We conclude galectin-12 negatively regulates macrophage polarization into the M2 population, resulting in enhanced inflammatory responses and also in turn causing decreased insulin sensitivity in adipocytes. This has implications in the treatment of a wide spectrum of metabolic disorders.
    Print ISSN: 0959-6658
    Electronic ISSN: 1460-2423
    Topics: Biology , Medicine
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  • 4
    Publication Date: 2012-07-07
    Description: Author(s): Yoko Kawamura, Kevin C. Y. Huang, Shruti V. Thombare, Shu Hu, Marika Gunji, Toyofumi Ishikawa, Mark L. Brongersma, Kohei M. Itoh, and Paul C. McIntyre We report observation of near-infrared photoluminescence from free-standing, vertically aligned germanium nanowires grown on a (111)-oriented silicon substrate. The energy of the photoluminescence peak is very close to that of the bulk crystalline germanium direct band gap. The intensity shows an ap... [Phys. Rev. B 86, 035306] Published Fri Jul 06, 2012
    Keywords: Semiconductors II: surfaces, interfaces, microstructures, and related topics
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 5
    Publication Date: 2014-01-19
    Description: [1]  We present results from an analysis of high-latitude ionosphere-thermosphere (IT) coupling to the solar wind during a moderate magnetic storm which occurred on 5-6 August 2011. During the storm, a multi-point set of observations of the ionosphere and thermosphere was available. We make use of ionospheric measurements of electromagnetic and particle energy made by the Defense Meteorological Satellite Program (DMSP), and neutral densities measured by the Gravity Recovery and Climate Experiment (GRACE) satellite to infer: (1) the energy budget and (2) timing of the energy transfer process during the storm. We conclude that the primary location for energy input to the IT system may be the extremely high latitude region. We suggest that the total energy available to the IT system is not completely captured either by observation or empirical models.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
    Publication Date: 2013-10-09
    Description: To overcome the deficiency of some current grid-/cell-based ray tracing algorithms, which are only able to handle first arrivals or primary reflections (or conversions) in anisotropic media, we have extended the functionality of the multistage irregular shortest-path method to 2-D/3-D tilted transversely isotropic (TTI) media. The new approach is able to track multiple transmitted/reflected/converted arrivals composed of any kind of combinations of transmissions, reflections and mode conversions. The basic principle is that the seven parameters (five elastic parameters plus two polar angles defining the tilt of the symmetry axis) of the TTI media are sampled at primary nodes, and the group velocity values at secondary nodes are obtained by tri-linear interpolation of the primary nodes across each cell, from which the group velocities of the three wave modes (q P , q SV and qSH ) are calculated. Finally, we conduct grid-/cell-based wave front expansion to trace multiple transmitted/reflected/converted arrivals from one region to the next. The results of calculations in uniform anisotropic media indicate that the numerical results agree with the analytical solutions except in directions of SV -wave triplications, at which only the lowest velocity value is selected at the singularity points by the multistage irregular shortest-path anisotropic ray tracing method. This verifies the accuracy of the methodology. Several simulation results show that the new method is able to efficiently and accurately approximate situations involving continuous velocity variations and undulating discontinuities, and that it is suitable for any combination of multiple transmitted/reflected/converted arrival tracking in TTI media of arbitrary strength and tilt. Crosshole synthetic traveltime tomographic tests have been performed, which highlight the importance of using such code when the medium is distinctly anisotropic.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 7
    Publication Date: 2008-10-22
    Description: Variable, diversity and joining (V(D)J) recombination and class-switch recombination use overlapping but distinct non-homologous end joining pathways to repair DNA double-strand-break intermediates. 53BP1 is a DNA-damage-response protein that is rapidly recruited to sites of chromosomal double-strand breaks, where it seems to function in a subset of ataxia telangiectasia mutated (ATM) kinase-, H2A histone family member X (H2AX, also known as H2AFX)- and mediator of DNA damage checkpoint 1 (MDC1)-dependent events. A 53BP1-dependent end-joining pathway has been described that is dispensable for V(D)J recombination but essential for class-switch recombination. Here we report a previously unrecognized defect in the joining phase of V(D)J recombination in 53BP1-deficient lymphocytes that is distinct from that found in classical non-homologous-end-joining-, H2ax-, Mdc1- and Atm-deficient mice. Absence of 53BP1 leads to impairment of distal V-DJ joining with extensive degradation of unrepaired coding ends and episomal signal joint reintegration at V(D)J junctions. This results in apoptosis, loss of T-cell receptor alpha locus integrity and lymphopenia. Further impairment of the apoptotic checkpoint causes propagation of lymphocytes that have antigen receptor breaks. These data suggest a more general role for 53BP1 in maintaining genomic stability during long-range joining of DNA breaks.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596817/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596817/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Difilippantonio, Simone -- Gapud, Eric -- Wong, Nancy -- Huang, Ching-Yu -- Mahowald, Grace -- Chen, Hua Tang -- Kruhlak, Michael J -- Callen, Elsa -- Livak, Ferenc -- Nussenzweig, Michel C -- Sleckman, Barry P -- Nussenzweig, Andre -- R01AI074953/AI/NIAID NIH HHS/ -- Z01 BC010283-10/Intramural NIH HHS/ -- Howard Hughes Medical Institute/ -- England -- Nature. 2008 Nov 27;456(7221):529-33. doi: 10.1038/nature07476. Epub 2008 Oct 19.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1360, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18931658" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apoptosis ; Chromosomal Proteins, Non-Histone ; DNA/genetics/*metabolism ; DNA Breaks ; DNA-Binding Proteins ; Gene Rearrangement, T-Lymphocyte/*genetics ; Genes, T-Cell Receptor alpha/genetics ; Genomic Instability ; Intracellular Signaling Peptides and Proteins/deficiency/genetics/*metabolism ; Lymphopenia/genetics/pathology ; Mice ; Models, Genetic ; Receptors, Antigen, T-Cell/genetics/metabolism ; *Recombination, Genetic ; Sequence Homology ; T-Lymphocytes/cytology/metabolism ; Thymus Gland/cytology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2019
    Description: Abstract The ionospheric response to explosions which occur at or below the Earth's surface has been noted since the first detonations of nuclear devices during the early period of aboveground testing. Acoustic gravity waves and traveling ionospheric disturbances were detected in association with test explosions carried out by the Union of Soviet Socialist Republics in Novaya Zemlya in 1961. While research in this area has continued, the standards accepted by the Comprehensive Nuclear Test Ban Treaty for detection and confirmation of nuclear explosions have been based on (1) seismic, (2) hydroacoustic, (3) infrasound, and (4) radionuclide monitoring from ground detectors. We suggest that ionospheric sensing offers a complementary methodology that may allow for robust confirmation of explosive events. One method of ionospheric monitoring of explosive events is analysis of total electron content (TEC), available by processing data from Global Navigation Satellite System (GNSS) receivers distributed globally on land masses. Traveling ionospheric disturbances observed by their signature in TEC have been used to detect and confirm mine collapses, mine blasts, earthquakes, volcanic eruptions, and meteorite strikes as well as underground nuclear tests. While an integrated measurement like TEC is not as sensitive to small‐amplitude density perturbations as other methods, the existence of large networks of continuously operating GNSS stations makes this an intriguing new monitoring asset. We report on the current capabilities for detection of explosions via the ionosphere, the outstanding challenges, and prospects for future developments that have potential to augment the current standards for detection and confirmation of nuclear detonations. By leveraging the worldwide network of GNSS receivers, robust confirmation of impulsive events is possible. This methodology complements existing technologies approved by the Comprehensive Test Ban Treaty. The article outlines background theory, new approaches to monitoring of explosions, and challenges that remain to be addressed.
    Print ISSN: 8755-1209
    Electronic ISSN: 1944-9208
    Topics: Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2009-04-25
    Description: Dual-process theories distinguish between intuition (fast and emotional) and reasoning (slow and controlled) as a basis for human decision-making. We contrast dominance-solvable games, which can be solved by step-by-step deliberative reasoning, with pure coordination games, which must be solved intuitively. Using functional magnetic resonance imaging, we found that the middle frontal gyrus, the inferior parietal lobule, and the precuneus were more active in dominance-solvable games than in coordination games. The insula and anterior cingulate cortex showed the opposite pattern. Moreover, precuneus activity correlates positively with how "effortful" a dominance-solvable game is, whereas insula activity correlates positively with how "effortless" a coordination game is.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kuo, Wen-Jui -- Sjostrom, Tomas -- Chen, Yu-Ping -- Wang, Yen-Hsiang -- Huang, Chen-Ying -- New York, N.Y. -- Science. 2009 Apr 24;324(5926):519-22. doi: 10.1126/science.1165598.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19390048" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*physiology ; Brain Mapping ; Decision Making/*physiology ; Female ; Frontal Lobe/physiology ; Games, Experimental ; Humans ; Intuition/*physiology ; Magnetic Resonance Imaging ; Male ; Memory/physiology ; Parietal Lobe/physiology ; Thinking/*physiology ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2015-01-17
    Description: The topology of the electronic structure of a crystal is manifested in its surface states. Recently, a distinct topological state has been proposed in metals or semimetals whose spin-orbit band structure features three-dimensional Dirac quasiparticles. We used angle-resolved photoemission spectroscopy to experimentally observe a pair of spin-polarized Fermi arc surface states on the surface of the Dirac semimetal Na3Bi at its native chemical potential. Our systematic results collectively identify a topological phase in a gapless material. The observed Fermi arc surface states open research frontiers in fundamental physics and possibly in spintronics.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xu, Su-Yang -- Liu, Chang -- Kushwaha, Satya K -- Sankar, Raman -- Krizan, Jason W -- Belopolski, Ilya -- Neupane, Madhab -- Bian, Guang -- Alidoust, Nasser -- Chang, Tay-Rong -- Jeng, Horng-Tay -- Huang, Cheng-Yi -- Tsai, Wei-Feng -- Lin, Hsin -- Shibayev, Pavel P -- Chou, Fang-Cheng -- Cava, Robert J -- Hasan, M Zahid -- New York, N.Y. -- Science. 2015 Jan 16;347(6219):294-8. doi: 10.1126/science.1256742. Epub 2014 Dec 18.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Joseph Henry Laboratory, Department of Physics, Princeton University, Princeton, NJ 08544, USA. Princeton Center for Complex Materials, Princeton Institute for Science and Technology of Materials, Princeton University, Princeton, NJ 08544, USA. ; Joseph Henry Laboratory, Department of Physics, Princeton University, Princeton, NJ 08544, USA. ; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA. ; Center for Condensed Matter Sciences, National Taiwan University, Taipei 10617, Taiwan. ; Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan. ; Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan. Institute of Physics, Academia Sinica, Taipei 11529, Taiwan. ; Department of Physics, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. ; Graphene Research Centre and Department of Physics, National University of Singapore 117542. ; Center for Condensed Matter Sciences, National Taiwan University, Taipei 10617, Taiwan. National Synchrotron Radiation Research Center, Taiwan. ; Joseph Henry Laboratory, Department of Physics, Princeton University, Princeton, NJ 08544, USA. Princeton Center for Complex Materials, Princeton Institute for Science and Technology of Materials, Princeton University, Princeton, NJ 08544, USA. mzhasan@princeton.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25593189" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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