Publication Date:
2001-02-24
Description:
The Arabidopsis genome project is the first to give a detailed picture of the centromeres in a higher eukaryote. The centromere, a crucial stretch of DNA buried in the knotty terrain at the center of the chromosome, has generally been ignored by other genome sequencing projects because it is highly repetitive, making it very difficult to sequence accurately. But the discovery of an Arabidopsis mutant whose pollen forms quartets has enabled the plant's centromeric regions to be defined with unprecedented accuracy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mlot, C -- New York, N.Y. -- Science. 2000 Dec 15;290(5499):2057-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11187825" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/*genetics/physiology
;
Cell Division
;
Centromere/*genetics/*physiology/ultrastructure
;
Chromosome Mapping
;
Chromosome Segregation
;
Chromosomes/physiology
;
Crosses, Genetic
;
DNA, Plant/genetics
;
*Genome, Plant
;
Meiosis
;
Mutation
;
Recombination, Genetic
;
Repetitive Sequences, Nucleic Acid
;
Sequence Analysis, DNA
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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