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  • 1
    Publication Date: 2014-11-04
    Description: The oxygenation of Earth’s atmosphere allowed for the diversification of metabolisms to include those that rely on oxygen and its derivatives. For example, chemolithotrophic oxidation of sulfide and iron both require oxygen or nitrate as terminal electron acceptors. A growing number of oxygen-utilizing chemolithotrophs are known to accumulate intracellular polyphosphate as an energy reserve that allows them to adapt to the fluctuating redox conditions in their distinctive-gradient habitats. Polyphosphate is also thought to play an important role in the formation of phosphatic mineral deposits. Here we present fossil evidence of iron-oxidizing bacteria preserved as filamentous iron oxides within phosphatic Paleoproterozoic stromatolites. The filaments include twisted stalks similar to those produced by modern iron-oxidizing bacteria that are known to metabolize polyphosphate and inhabit steep redox gradients. Fossil iron-oxidizing bacteria preserved within some of the oldest known phosphorites serve as indicators of O 2 -Fe(II) gradients that may have supported microbially mediated phosphogenesis via polyphosphate metabolism and/or an active iron redox pump.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 2
    Publication Date: 1992-05-01
    Description: The long-term facilitation of synaptic efficacy that is induced by serotonin in dissociated cell cultures of sensory and motor neurons of Aplysia is accompanied by the growth of new synaptic connections. This growth is associated with a down-regulation in the sensory neuron of Aplysia cell adhesion molecules (apCAMs). To examine the mechanisms of this down-regulation, thin-section electron microscopy was combined with immunolabeling by gold-conjugated monoclonal antibodies specific to apCAM. Within 1 hour, serotonin led to a 50% decrease in the density of gold-labeled complexes at the surface membrane of the sensory neuron. This down-regulation was achieved by a heterologous, protein synthesis-dependent activation of the endosomal pathway, which leads to internalization and apparent degradation of apCAM. The internalization is particularly prominent at sites where the processes of the sensory neurons contact one another and may act there to destabilize process-to-process contacts that normally inhibit growth. In turn, the endocytic activation may lead to a redistribution of membrane components to sites where new synapses form.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailey, C H -- Chen, M -- Keller, F -- Kandel, E R -- GM32099/GM/NIGMS NIH HHS/ -- MH37134/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1992 May 1;256(5057):645-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, NY.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1585177" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anisomycin/pharmacology ; Antibodies, Monoclonal ; Aplysia/*physiology ; Cell Adhesion Molecules/*metabolism ; Cell Membrane/metabolism/ultrastructure ; Cells, Cultured ; Coated Pits, Cell-Membrane/metabolism/ultrastructure ; Endocytosis/*drug effects ; Immunohistochemistry ; Microscopy, Electron ; Motor Neurons/physiology/ultrastructure ; Neurons, Afferent/physiology/ultrastructure ; Serotonin/*pharmacology ; Synapses/*physiology/ultrastructure ; Wheat Germ Agglutinins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1983-04-01
    Description: The morphological basis of the persistent synaptic plasticity that underlies long-term habituation and sensitization of the gill withdrawal reflex in Aplysia californica was explored by examining the fine structure of sensory neuron presynaptic terminals (the critical site of plasticity for the short-term forms of both types of learning) in control animals and in animals whose behavior had been modified by training. The number, size, and vesicle complement of sensory neuron active zones were larger in animals showing long-term sensitization than in control animals and smaller in animals showing long-term habituation. These changes are likely to represent an anatomical substrate for the memory consolidation of these tasks.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailey, C H -- Chen, M -- GM23540/GM/NIGMS NIH HHS/ -- MH37134-01/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1983 Apr 1;220(4592):91-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6828885" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aplysia/*physiology ; Gills/innervation ; Habituation, Psychophysiologic/*physiology ; Neuronal Plasticity ; Neurons, Afferent/physiology ; Reflex/physiology ; Synapses/ultrastructure ; Synaptic Vesicles/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 42 (1920), S. 45-48 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 58 (1936), S. 383-390 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 58 (1936), S. 390-393 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 55 (1933), S. 1981-1988 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 49 (1945), S. 261-261 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 14 (1922), S. 147-150 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 25 (1933), S. 437-440 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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