Publication Date:
2016-11-22
Description:
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry Nature Communications, Published online: 21 November 2016; doi:10.1038/ncomms13404 Neoantigens determine anti-cancer immunoreactivity and are important functional targets for immunotherapy. Here, the authors use deep mass spectrometry to characterize neoepitopes from human melanoma tissue and show the presence of tumour-reactive T cells with specificity for selected neoantigens.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink