Publication Date:
2013-09-12
Description:
Key Points TLR-stimulated macrophages synthesize, release, and hydrolyze ATP via CD39 to regulate their own activation state. The loss of macrophage CD39 prevents regulatory macrophage development and leads to lethal inflammatory responses and septic shock in mice.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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