Electronic Resource
Springer
Journal of molecular evolution
6 (1975), S. 199-207
ISSN:
1432-1432
Keywords:
Prebiotic
;
Synthesis
;
Nucleotides
;
Oligonucleotides
;
Cyanamide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary A reaction which oligomerizes nucleotides under possible prebiotic conditions has been characterized. Nucleoside monophosphate in the presence of cyanamide at acid pH condenses to form dithymidine pyrophosphate and phosphodiester bonded compounds. Imidazole compounds and activated precursors such as nucleoside triphosphate are not necessary for this oligomerization reaction which produces primarily cyclic oligonucleotides.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01732356
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