ISSN:
1612-1112
Keywords:
Capillary electrochromatography
;
Packed capillaries
;
Buffer depletion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Capillary electrochromatography is an emerging technique utilising small diameter capillaries (typically 50 μm) packed with HPLC-type stationary phases. Using electrically driven flow, higher efficiencies can be obtained than with pumped flow. This paper discusses some important points to enable more efficient, reliable capillaries to be prepared and also offers some suggestions regarding more suitable choices of mobile phase buffer which suffer less “depletion” problems than those buffers used to date. Separations of some drug candidates are shown and the future development of this technique is briefly discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02290365
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