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  • 1
    Electronic Resource
    Electronic Resource
    Mutagenic activity associated with cooling tower waters treated with a biocide containing 5-chloro-2-methyl-4-isothiazolin-3-one (1987)
    s.l. : American Chemical Society
    Environmental science & technology 21 (1987), S. 815-820 
    Details
    ISSN: 1520-5851
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/es00162a014
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  • 2
    Electronic Resource
    Electronic Resource
    Nitrosated methylcarbamate insecticides: Effect on the DNA of human cells
    Amsterdam : Elsevier
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 44 (1977), S. 1-7 
    Details
    ISSN: 0027-5107
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0027-5107(77)90109-9
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  • 3
    Electronic Resource
    Electronic Resource
    Mutagenicity screening of five methyl carbamate insecticides and their nitroso derivatives using mutants of Salmonella typhimurium LT2
    Amsterdam : Elsevier
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 56 (1977), S. 1-6 
    Details
    ISSN: 0027-5107
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0027-5107(77)90234-2
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  • 4
    Electronic Resource
    Electronic Resource
    Least-squares refinement of two protein molecules per asymmetric unit with and without non-crystallographic symmetry restrained (1986)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 198-200 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010876818609835X
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  • 5
    Electronic Resource
    Electronic Resource
    Soil Carbon Dynamics in Corn-Based Agroecosystems: Results from Carbon-13 Natural Abundance (1999)
    Springer
    Soil Science Society of America journal 63 (1999), S. 584-591 
    Details
    ISSN: 1435-0661
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: 13 C abundance in soils to calculate the fate of C4-C inputs in fields cropped to continuous corn (Zea mays L.). Soil samples were collected from eight cultivated and six adjacent noncultivated sites of the Corn Belt region of the central USA. The amount of organic C in cultivated soils declined an average of 68%, compared with adjacent, noncultivated sites. The δ13C of cultivated soil profiles that had been under continuous corn for 8 to 35 yr increased in all depth increments above that of the noncultivated profiles. The percentage of soil organic C (SOC) derived from corn residues and roots ranged from 22 to 40% of the total C. The proportion of corn-derived C, as determined by this technique, decreased with soil depth and was minimal in the 50- to 100-cm depth increments of fine-textured soils. The mean residence time of the non-corn C (C3) ranged from 36 to 108 yr at the surface, and up to 769 yr at the subsoil depth. The longer turnover times were associated with soils high in clay. Prairie-derived soils have a higher potential to sequester C than those derived from forests. The significant loss of total C at all sites and the slow turnover times of the incorporated C lead us to conclude that there is a substantial potential for soils to serve as a C sink and as a significant nutrient reserve in sustainable agriculture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
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  • 6
    Electronic Resource
    Electronic Resource
    Residual Stress Measurements in Australia: Present and Future (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 490-491 (July 2005), p. 218-222 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The Australian Nuclear Science and Technology Organisation, ANSTO,(http:\\www.ansto.gov.au) has initiated a “Neutrons for Engineering” project to provide an integrated residual stress service to Australian industry and academia. The service is based around measurements of residual stress using neutrons on a newly-refurbished instrument on the HIFAR research reactor. In addition to the neutron measurements there is a range of expertise available on the ANSTO site to solve residual stress problems using other techniques including hole-drilling, strain-gauging, and x-ray diffraction, as well as capabilities for finite element modeling andmechanical testing. In this paper we describe briefly the existing and future facilities at ANSTO for neutron strain scanning and present some benchmark results for the HIFAR strain scanner
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/10/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.490-491.218.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    2,3,7,8 Tetrachlorodibenzodioxin in fish from the pigeon river of Eastern Tennessee, USA: Its toxicity and mutagenicity as revealed by the Ames Salmonella assay (1991)
    Springer
    Archives of environmental contamination and toxicology 20 (1991), S. 366-370 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Levels of 2,3,7,8 tetrachlorodibenzodioxin (TCDD) were determined in both striated muscle (fillets) and whole body extracts of fish specimens harvested during a two-year period (1987–1989) from the Pigeon River (between Hartford and Newport) of Eastern Tennessee (USA). Whole body (wet weight) fish extract levels as high as 117 μg/kg body weight and composite fish fillet (wet weight) extract levels as high as 87 μg/kg fillet weight were observed. Pure TCDD was found to be highly toxic to theSalmonella typhimurium strains TA97, TA98, and TA100 at dosages which exceeded 825 ng TCDD/ml in the top agar of the Ames Salmonella assay. An 825 ng/ml TCDD dosage was not mutagenic to any of the tested Salmonella strains, either with or without metabolic activation (S9 mix). However, when acidic fish extracts from the Pigeon River were tested for mutagenicity, most of the fish extracts were mutagenic to Salmonella strains TA97, TA98, and TA100. These mutagenic extracts also demonstrated mutagenic dose-response curves. Other chemicals within the extracts as well as synergistic effects may account for the mutagenicity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01064404
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  • 8
    Electronic Resource
    Electronic Resource
    Heavy metal Concentrations in the Holston River Basin (Tennessee) (1981)
    Springer
    Archives of environmental contamination and toxicology 10 (1981), S. 541-560 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Contamination levels of zinc, cadmium, mercury, copper, lead, and manganese of the major streams in the Holston River Basin in Eastern Tennessee are reported and compared with other waterways. Heavy metal levels are sufficiently high in areas of the Basin to affect the health of aquatic life. The levels of cadmium, copper, manganese, lead and zinc were measured in fish samples from each lake and stream in the Basin and compared to those reported for fish throughout the world. The use of fish to monitor the levels of heavy metals is discussed as an alternative to grab samples of water; mercury levels in fish muscle reflected pollution of a stream, whereas grab samples of water did not.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01054878
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  • 9
    Electronic Resource
    Electronic Resource
    Mutagenic activity of surface waters adjacent to a nuclear fuel processing facility (1987)
    Springer
    Archives of environmental contamination and toxicology 16 (1987), S. 531-537 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Surface waters adjacent to a nuclear fuel processing facility were extracted, using XAD-resin adsorption followed by solvent elution, and the extracts were assayed for mutagenic potential by the AmesSalmonella-mammalian microsome test. Dose-related mutagenic responses with TA102 (+ S9) were produced with the extracts of water samples obtained from a creek receiving waste-water from the processing facility (specific mutagenic activities of 7,250 to 8,250 net revertants per L equivalent of water). The creek water extracts were not mutagenic with TA102 in the absence of S9, or with any other tester strain (i.e., TA97, TA98, TA100, and TA1535) in the presence or absence of S9. Surface water samples downstream and upstream of this creek were not mutagenic; apparently indicating the lack of persistence of the observed mutagenicity. The major constituent in the mutagenic creek water extracts was identified as tributylphosphate (TBP) by gas chromatography-mass spectrometry. However, TBP was not mutagenic with TA102 (+ S9) at doses ranging from 196 μg/plate to 9.8 ng/plate. Because tester strain TA102 detects oxidative mutagenesis due to x-rays and ultraviolet radiation, it is possible that the observed mutagenicity of creek water extracts was due to radionuclides complexed to TBP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01055809
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  • 10
    Electronic Resource
    Electronic Resource
    Chemically-induced histone modification as a predictor of carcinogenicity (1993)
    Springer
    Archives of environmental contamination and toxicology 25 (1993), S. 260-266 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract The interaction between carcinogens and DNA is believed to initiate neoplastic transformation, but evidence suggests that epigenetic mechanisms may also be of importance. Because the histone proteins have important roles in chromatin structure and cellular function, they provide a reasonably well understood epigenetically-based system for the detection of carcinogens. In this study, human foreskin fibroblastic cells were exposed to one of several mutagens and/or carcinogens for 3, 12, or 24 h to determine if induced histone modification may be a means of predicting chemical carcinogenicity. Butyric acid (5 mM), known to result in acetylation of histones H3 and H4, and 12-O-tetradecanoylphorbol-13-acetate (3 μM), known to result in phosphorylated histone H1, were tested initially. Electrophoresis of the histone fractions was capable of resolving multiple forms of histones H1, H3, and H4. Propane sultone (0.1 mM) induced a broadening of the H2A and H2B bands after a 24 h exposure and carbon tetrachloride (1 mM) induced the formation of new histone forms in the H1 fraction after 24 h and in the H3 fraction after 3 h. Experimental variability limited the statistically significant modifications to carbon tetrachloride and propane sultone, two known carcinogens, where new forms of modified histone were detected. Therefore, the histone modification assay, with further experimentation, may be an alternate method of detecting carcinogens, especially when conventional genotoxic tests prove unreliable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00212139
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