ISSN:
1749-6632
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Natural Sciences in General
Notes:
One or more electrophoretically unusual isozymes of LDH have been demonstrated in homogenates of mature testes from some species. Analyses of the isozymic composition of many other tissues, developing testes, and seminal fluid revealed that these unusual forms, or “band X” isozymes, are present only in postpubertal testes and are localized in the differentiating germ cells of the seminiferous tubules. Rates of reactivity with certain alpha-hydroxy acids and analogs of nicotinamide adenine dinucleotide differentiated some of the “band X” isozymes from the usual LDH isozymes. Results of dissociation and recombination studies on homogenates of human and rabbit testes indicated a similarity in structure between “band X” and the other isozymes.The ontogeny and characteristic distribution of the “band X” isozymes suggested that each fulfills a specific metabolic function. As yet the nature of this metabolic assignment has not been determined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1749-6632.1964.tb14227.x
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