ISSN:
1522-9602
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Mathematics
Notes:
Abstract Parallel computation employing a domain decomposition method was used to calculate precisely without approximations the spatio-temporal distribution of Ca2+ in nerve terminals. The results showed, contrary to expectations, that for equal admitted Ca2+ currents at low (one channel open) and high (four channels open) depolarization, the average Ca2+ concentration at the release area is higher at the low depolarization. These calculations provide additional support for the Ca2+-voltage hypothesis for neurotransmitter release.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02458384
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