ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
The presence of opioid, β-adrenergic and cholinergic receptors has been demonstrated in ciliated protozoa, but little is known about γ-aminobutyric acid (GABA) receptors. In this study we have analyzed the distribution of GABAA-type receptor subunits in Paramecium. Confocal laser microscopy using antibodies specific for α1-, α2-, α3-, α6-, β2/3-, γ2-, ε-, λ-, and θ-subunits showed that most receptors are aggregated in clusters and are distributed both on cell surface and in the cytoplasm. The intensity of labelling of the α6-, β2/3- and γ2-subunits was more intense than the α1-, ε-, and θ-subunits, suggesting that the former are present in higher concentrations than the latter.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.2004.tb09788.x
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