ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Previous studies with GH3 and other cell types have demonstrated that the cell-bound 125I-EGF is rapidly degraded (fi/2 = 20 min) to mono-125I-iodotyrosine by lysosomal proteases following endocytotic internalization6'1112. Due to this process, the intracellular amount of intact EGF reaches, within ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/287340a0
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