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  • 1
    Electronic Resource
    Electronic Resource
    Seismic reflection images of the Moho underlying melt sills at the East Pacific Rise (2006)
    [s.l.] : Nature Publishing Group
    Nature 442 (2006), S. 287-290 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The determination of melt distribution in the crust and the nature of the crust–mantle boundary (the ‘Moho’) is fundamental to the understanding of crustal accretion processes at oceanic spreading centres. Upper-crustal magma chambers have been imaged beneath fast- and intermediate-spreading ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature04939
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  • 2
    Electronic Resource
    Electronic Resource
    Evidence from three-dimensional seismic reflectivity images for enhanced melt supply beneath mid-ocean -ridge discontinuities (2000)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 406 (2000), S. 614-618 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Quantifying the melt distribution and crustal structure across ridge-axis discontinuities is essential for understanding the relationship between magmatic, tectonic and petrologic segmentation of mid-ocean-ridge spreading centres. The geometry and continuity of magma bodies beneath ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/35020543
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  • 3
    Electronic Resource
    Electronic Resource
    LISPB revisited: a new look under the Caledonides of northern Britain (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 110 (1992), S. 0 
    Details
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: The Lithospheric Seismic Profile in Britain (LISPB), shot in 1974, included a 700 km long north-south profile of the crust and upper mantle of northern Britain. The wide-angle seismic data from LISPB was of exceptional quality and coverage making a reinterpretation using current modelling programs worthwhile. This reinterpretation shows that the original crustal model published by Bamford et al. (1978) satisfies the observed first arrival traveltimes, but that further detail of crustal velocity structure may be obtained by model shows strong variations in crustal velocity structure that appear to be correlated with geological and tectonic structures mapped at the surface. The new lithospheric model is compatible with the observed gravity field when converted to appropriate densities, and the variations in loading along the base of the density model show that the lithosphere is close to local isostatic equilibrium. Profiles of the variation of velocity and density with depth from the new model are compared with measurements of Lewisian rocks made at confining pressures up to 8 kbar, allowing the seismic model to be interpreted geologically. A synthetic normal incidence profile of the new model is superimposed on the nearby NEC deep seismic reflection profile, and the features imaged by the two techniques are compared.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-246X.1992.tb00881.x
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  • 4
    Electronic Resource
    Electronic Resource
    Crustal structure of the Madeira–Tore Rise, eastern North Atlantic—results of a DOBS wide-angle and normal incidence seismic experiment in the Josephine Seamount region (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 106 (1991), S. 0 
    Details
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: During November–December 1988, an extensive geophysical data set was collected over the Josephine Seamount, which is located at the northeasterly end of the Madeira–Tore Rise in the eastern North Atlantic. The Josephine Seamount lies at the intersection of the Madeira–Tore Rise and Azores–Gibraltar Fracture Zone, the latter representing the Africa–Eurasia plate boundary in this part of the eastern North Atlantic. From this data set, a 275 km long explosive refraction line has been modelled together with wide-angle airgun profiles, seismic reflection and gravity data. The velocity–depth model shows that the crust either side of the Seamount is typically oceanic in character. However, beneath the Seamount there exists a region of anomalously high velocity and crustal thickening to a depth of about 17–18 km. Gravity modelling also suggests that the Josephine Seamount is compensated by a crustal root, and that the Josephine Seamount/Madeira–Tore Rise system is in local isostatic equilibrium. Calculations of the flexural rigidity and effective elastic thickness of the lithosphere in this region suggest that the Madeira–Tore Rise formed contemporaneously with the lithosphere on which it lies. This age of crustal loading is consistent with the proposal that the Madeira–Tore Rise is an aseismic ridge which formed at or near the Mid-Atlantic Ridge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-246X.1991.tb03898.x
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  • 5
    Electronic Resource
    Electronic Resource
    The Hatton Bank continental margin—III. Structure from wide-angle OBS and multichannel seismic refraction profiles (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 98 (1989), S. 0 
    Details
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: In two recent papers, normal incidence and expanding spread profiles (ESPs) shot across the Hatton Bank passive continental margin showed seaward dipping reflectors in the upper crust and elevated velocities in the lower crust. The reflectors were interpreted as subaerial basalt flows and the high velocities as underplated or intruded igneous material in the lower crust. A recent gravity model shows high densities in the lower crust supporting the velocity model. In this study we present the forward modelling of two wide-angle seismic refraction datasets shot perpendicular to strike and through the ESP midpoints. The final velocity model across the margin is consistent with all the seismic datasets but differs in some important respects from the ESP-based model: a high velocity volcanic pile is outlined mid-way up the continental slope and the inferred velocities in the lower crust are slightly lower. The differences between the two models can be explained by the three-dimensional nature of the margin: the ESPs were modelled assuming that the sub-sediment structure was invariant along strike. The final velocity model is used to obtain an estimate of the total thickness of melt accreted across the margin, which is calculated to thicken from zero at Hatton Bank to about 12km mid-way down the continental slope. At the bottom of the continental slope the adjacent igneous section forming the oceanic crust is about 18 km thick and thins rapidly northwestwards to 11 km. As the oceanic crust thins its seismic velocity decreases; this suggests that it is less mafic and that there is a post-rift decrease in the percentage of mantle melting. This decrease may be explained by a decrease in asthenospheric temperature and/or by a reduction in volatile content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-246X.1989.tb03358.x
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  • 6
    Electronic Resource
    Electronic Resource
    Southern Segment of the European Geotraverse — a wide-angle seismic refraction experiment in the Sardinia Channel (1992)
    Springer
    Marine geophysical researches 14 (1992), S. 227-248 
    Details
    ISSN: 1573-0581
    Keywords: OBS ; thinned continental crust ; seismic structure ; Sardinia Channel ; rifted continental margin ; European Geotraverse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The Sardinia Channel dataset was collected as part of the European Geotraverse (EGT)—a 4000 km seismic refraction line running from Northern Norway to the Sahara, designed to investigate the structure of the lithosphere beneath Europe. Wideangle seismic data recorded by ocean bottom seismometers deployed in the Sardinia Channel as part of the Southern Segment of the EGT, together with gravity data, were used to constrain the final crustal model. In the centre of the Channel the crust is identified as thinned continental in nature, with a crystalline thickness of 10 km overlain by 4 km of sediments and 2.5 km of water in the most extended region. High velocities in the lower crust in the central region are thought to represent an area of underplating or intrusion by igneous material caused by extension related to the opening of the Tyrrhenian Sea. The crust overlies an anomalously low velocity upper mantle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01270631
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  • 7
    Electronic Resource
    Electronic Resource
    The same myosin alkali light chain gene is expressed in adult cardiac atria and in fetal skeletal muscle (1985)
    Springer
    Journal of muscle research and cell motility 6 (1985), S. 461-475 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We have isolated from a cDNA library constructed using mouse cardiac mRNA sequences, a clone (pC6) homologous to part of the mRNA encoding the myosin alkali light chain MLC1A from adult mouse atria. This sequence also hybridizes to mRNA encoding the fetal light chain form MLC1emb expressed in both fused myotubes in culture and in 18 day fetal skeletal muscle. These mRNA sequences are indistinguishable from the MLC1A messenger both on the basis of size and of their thermal stability of hybridization.In vitro translation of mRNA selected by hybridization with pC6 results in a protein that comigrates with the fetal MLC1emb isoform, and two-dimensional gel electrophoresis of adult atrial and fetal skeletal muscle proteins shows MLC1A and MLC1emb to be indistinguishable in the mouse. Southern blot hybridization of clone pC6 to mouse genomic DNA and the analysis of restriction fragment length polymorphisms between different mouse species demonstrates the presence of a single hybridizing locus in the mouse genome. These data provide strong evidence that the atrial MLC1A and fetal skeletal MLC1emb isoform are encoded by the same gene and by the same mRNA and are thus identical proteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00712583
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  • 8
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    Search for Neutrinoless Double- β Decay in Ge76 with the Majorana Demonstrator (2018)
    American Physical Society
    Details
    Publication Date: 2018-03-26
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
    Published by American Physical Society
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  • 9
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    FineSplice, enhanced splice junction detection and quantification: a novel pipeline based on the assessment of diverse RNA-Seq alignment solutions (2014)
    Oxford University Press
    Details
    Publication Date: 2014-05-01
    Description: Alternative splicing is the main mechanism governing protein diversity. The recent developments in RNA-Seq technology have enabled the study of the global impact and regulation of this biological process. However, the lack of standardized protocols constitutes a major bottleneck in the analysis of alternative splicing. This is particularly important for the identification of exon–exon junctions, which is a critical step in any analysis workflow. Here we performed a systematic benchmarking of alignment tools to dissect the impact of design and method on the mapping, detection and quantification of splice junctions from multi-exon reads. Accordingly, we devised a novel pipeline based on TopHat2 combined with a splice junction detection algorithm, which we have named FineSplice. FineSplice allows effective elimination of spurious junction hits arising from artefactual alignments, achieving up to 99% precision in both real and simulated data sets and yielding superior F 1 scores under most tested conditions. The proposed strategy conjugates an efficient mapping solution with a semi-supervised anomaly detection scheme to filter out false positives and allows reliable estimation of expressed junctions from the alignment output. Ultimately this provides more accurate information to identify meaningful splicing patterns. FineSplice is freely available at https://sourceforge.net/p/finesplice/ .
    Keywords: Computational Methods, Massively Parallel (Deep) Sequencing, Genomics
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 10
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    Shifted-elliptical nonstretch moveout correction of wide-angle seismic data in the Formula domain, using an example from the Faeroe-Shetland Basin (2012)
    Society of Exploration Geophysicists (SEG)
    Details
    Publication Date: 2012-10-25
    Description: We developed a method of moveout correction in the $$\tau \hbox{ - }p$$ domain to tackle some of the problems associated with processing wide-angle seismic reflection data, including residual moveout and normal-moveout stretching. We evaluated the concept of the shifted ellipse in the $$\tau \hbox{ - }p$$ domain as an alternative to the well-known concept of the shifted hyperbola in the $$t\hbox{ - }x$$ domain. We used this shifted-ellipse concept to address the problem of residual moveout caused by vertical heterogeneity in the subsurface. We also addressed the stretching problem associated with dynamic corrections by combining selected strips from a set of constant-moveout stacks generated using a shifted-ellipse equation. Application of this method to a wide-angle data set from the Faeroe-Shetland Basin provided an enhanced image of the subbasalt structure.
    Print ISSN: 0016-8033
    Electronic ISSN: 1942-2156
    Topics: Geosciences , Physics
    Published by Society of Exploration Geophysicists (SEG)
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