Publication Date:
1984-03-23
Description:
An assay for antibodies to membrane antigens of cells infected by human T-cell leukemia virus was used to examine serum from persons who donated blood to 12 patients with acquired immunodeficiency syndrome (AIDS) associated with blood transfusions. The occurrence of positive results in the assay was significantly greater among donors to the AIDS patients (9 of 117; 7.7 percent) than among random donors (1 of 298; 0.3 percent). Of 12 sets of donors examined, 9 sets included a donor whose serum gave positive results for the presence of the antibodies. In six of these nine sets, the seropositive donor was an individual who was also identified as a possible source of AIDS transmission when epidemiologic and immunologic criteria were used.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jaffe, H W -- Francis, D P -- McLane, M F -- Cabradilla, C -- Curran, J W -- Kilbourne, B W -- Lawrence, D N -- Haverkos, H W -- Spira, T J -- Dodd, R Y -- New York, N.Y. -- Science. 1984 Mar 23;223(4642):1309-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322301" target="_blank"〉PubMed〈/a〉
Keywords:
Acquired Immunodeficiency Syndrome/*etiology/immunology/transmission
;
Adult
;
Aged
;
Antibodies, Viral/*analysis
;
Antigens, Surface/immunology
;
Antigens, Viral/immunology
;
*Blood Donors
;
Blood Transfusion/*adverse effects
;
Deltaretrovirus/immunology/*pathogenicity
;
Female
;
Homosexuality
;
Humans
;
Male
;
Middle Aged
;
Retroviridae/*immunology
;
Retroviridae Infections/*epidemiology
;
Risk
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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