Publication Date:
2004-01-13
Description:
Over a century ago, Freud proposed that unwanted memories can be excluded from awareness, a process called repression. It is unknown, however, how repression occurs in the brain. We used functional magnetic resonance imaging to identify the neural systems involved in keeping unwanted memories out of awareness. Controlling unwanted memories was associated with increased dorsolateral prefrontal activation, reduced hippocampal activation, and impaired retention of those memories. Both prefrontal cortical and right hippocampal activations predicted the magnitude of forgetting. These results confirm the existence of an active forgetting process and establish a neurobiological model for guiding inquiry into motivated forgetting.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, Michael C -- Ochsner, Kevin N -- Kuhl, Brice -- Cooper, Jeffrey -- Robertson, Elaine -- Gabrieli, Susan W -- Glover, Gary H -- Gabrieli, John D E -- MH59940/MH/NIMH NIH HHS/ -- MH62126/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 2004 Jan 9;303(5655):232-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, University of Oregon, Eugene, OR 97403, USA. mcanders@darkwing.uoregon.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14716015" target="_blank"〉PubMed〈/a〉
Keywords:
Adult
;
Brain Mapping
;
Cues
;
Female
;
Gyrus Cinguli/physiology
;
Hippocampus/*physiology
;
Humans
;
Magnetic Resonance Imaging
;
*Memory
;
Mental Recall
;
Prefrontal Cortex/*physiology
;
*Repression, Psychology
;
Retention (Psychology)
;
Temporal Lobe/physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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