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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 1052 (1990), S. 71-77 
    ISSN: 0167-4889
    Keywords: Heat-shock protein ; Methionine-free solution ; Nucleoli
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 19 (1990), S. 395-399 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The primary structures of unknown cyclic peptides produced by a Bacillus strain have been determined by fast atom bombardment (FAB) mass spectrometry, which has established the peptides as a new family of the iturin group antibiotics. FAB mass spectra of the intact peptides gave the immonium ions characteristic of constituent amino acids which made it possible to distinguish Asn from Asp and Glu from Gln. Collision-induced dissociation (CID) spectra of protonated molecules provided complete information on the connectivity of amino acid residues but did not reveal the direction of peptide bonding, while those obtained for fragment ions allowed us to make a discrimination between the correct sequence and its retro sequence. The amino acid sequences derived are c(Thr-Xaa-Asn-Tyr-Asn-Ser-Glu-Ser) (Xaa: C14 or C15 β-amino acid) which are closely related to that of bacillomycin L. The structure is confirmed by the FAB mass spectra of the partial acid hydrolysate and the peptide mixture obtained from its single-step Edman degradation. Fragmentation processes involved in the CID spectra of the cyclic peptides are discussed based on the established amino acid sequence.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2003-03-01
    Print ISSN: 0034-6748
    Electronic ISSN: 1089-7623
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
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  • 4
    Publication Date: 2013-06-08
    Description: A crustal normal-faulting earthquake ( ; M w  6.7) occurred in eastern Tohoku, Japan, on 11 April 2011. K-NET and KiK-net stations recorded 82 records from within 100 km of fault rupture. These data and data from associated foreshocks and aftershocks will make a critical contribution to future improvements of ground-motion prediction for normal-faulting earthquakes. Peak ground accelerations (PGA) and peak ground velocities (PGV) are compared with four ground-motion prediction equations (GMPEs) that include the style of faulting as a predictor parameter. For distances under 100 km, and using a network average value of V S 30 , the average ratio of PGA to the selected GMPEs (the event term ) is high by factors of 2.3–3.7. Event terms for PGV are high by factors of 1.4–1.8. Adjusting PGA and PGV with customized site terms ( Kawase and Matsuo, 2004a , b ), the standard deviations of PGA and PGV residuals are reduced from 0.59 to 0.43, and from 0.53 to 0.35, respectively. The event terms decreased to relatively small factors of 1.1–1.8 for PGA and increased slightly to 1.5–2.0 for PGV. Thus, site terms are very important, but positive event terms remain. The remaining positive event terms are not explained by high stress drop, which was typical of crustal events of all mechanisms globally or in Japan. Two subparallel faults ruptured, but source inversions, which we reviewed, revealed that they ruptured sequentially, so simultaneous contributions from the two faults did not cause high motions. Although these observations may tend to suggest that ground motions in large normal-faulting events are larger than predicted by the tested models, we are not aware of any observations from this event that contradict the precarious rock evidence of Brune (2000) that ground shaking is low on the footwall near the rupture.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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  • 5
    Publication Date: 2016-04-07
    Description: We present a new approach for broadband ground-motion simulation that is a combination of high-frequency (HF, f 〉0.5 Hz) and low-frequency (LF, f 〈0.5 Hz) ground-motion simulations. In this method, the LF ground motion is first computed by a deterministic approach based on a velocity model and a source model. Then, the HF acceleration envelopes are computed by multiplying the LF envelopes by envelope ratio functions (ERFs), which are defined as the empirical relationships between the characteristics of envelopes of different frequency bands. We apply the method to the 2003 Tokachi-Oki, Japan, earthquake ( M w  8.3). The LF ground motion is computed by a finite-difference method with a 3D velocity model and a finite-fault slip model. Because of the complicated rupture process of the earthquake, the fault is divided into subfaults that can be considered as smaller earthquakes. ERFs are estimated by investigating the ground-motion data of moderate-size aftershocks (5.4≤ M w ≤6.6) for each station. The HF ground motions are simulated using the LF ground motion and the ERFs. Seismograms of all frequency bands are summed to give a time series of broadband (0.05–16 Hz) ground motion. We find that our method yields realistic broadband ground motion, in terms of the acceleration envelope, velocity waveform, and Fourier amplitude spectrum. Comparing the HF waveforms with those computed by the stochastic Green’s function method (SGFM), we find that the performance of our method is better than that of the SGFM under the condition that LF waveforms are appropriately computed. The proposed method has the potential to be used as a practical method for broadband ground-motion prediction incorporating the effects of a 3D velocity model and a finite-source model. Online Material: Figures comparing simulated and observed low-frequency waveforms and root mean square acceleration envelopes in different frequency ranges.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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  • 6
    Publication Date: 2016-01-30
    Description: Human quiet standing is accompanied by body sway. The amplitude of this body sway is known to be larger than would be predicted from simple noise effects, and sway characteristics are changed by neurological disorders. This large sway is thought to arise from nonlinear control with prolonged periods of no control (intermittent control), and a nonlinear control system of this kind has been predicted to exhibit bifurcation. The presence of stability-dependent transition enables dynamic reaction that depends on the stability of the environment, and can explain the change in sway characteristics that accompanies some neurological disorders. This research analyses the characteristics of a system model that induces transition, and discusses whether human standing reflects such a mechanism. In mathematical analysis of system models, (intermittent control-like) nonlinear control with integral control is shown to exhibit Hopf bifurcation. Moreover, from the analytical solution of the system model with noise, noise is shown to work to smooth the enlargement of sway around the bifurcation point. This solution is compared with measured human standing sway on floors with different stabilities. By quantitatively comparing the control parameters between human observation and model prediction, enlargement of sway is shown to appear as predicted by the model analysis.
    Keywords: robotics, biomechanics, cybernetics
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 7
    Publication Date: 2016-01-30
    Description: In the estimation of spatiotemporal slip models, kinematic source inversions using Akaike's Bayesian Information Criterion (ABIC) and the multiple-time-window method have often been used. However, there are cases in which conventional ABIC-based source inversions do not work well in the determination of hyperparameters when a non-negative slip constraint is used. In order to overcome this problem, a new source inversion method was developed in this study. The new method introduces a fully Bayesian method into the kinematic multiple-time-window source inversion. The multiple-time-window method is one common way of parametrizing a source time function and is highly flexible in terms of the shape of the source time function. The probability distributions of model parameters and hyperparameters can be directly obtained by using the Markov chain Monte Carlo method. These probability distributions are useful for simply evaluating the uniqueness and reliability of the derived model, which is another advantage of a fully Bayesian method. This newly developed source inversion method was applied to the 2011 Ibaraki-oki, Japan, earthquake ( M w 7.9) to demonstrate its usefulness. It was demonstrated that the problem with using the conventional ABIC-based source inversion method for hyperparameter determination appeared in the spatiotemporal source inversion of this event and that the newly developed source inversion could overcome this problem.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 8
    Publication Date: 2012-07-03
    Description: The M9.0 Tohoku-oki event is the largest earthquake in Japan's modern history. Social concerns and scientific interests require an urgent evaluation of this event's impact on other megathrust zones nearby Japan. Here we investigate the stress transfer from the Tohoku-oki event on the Tokai subduction zone, where an M8-class megathrust earthquake has been long-time anticipated. First we demonstrate that the clear increase of crustal seismicity around Izu Peninsula, near the Tokai gap, is the consequence of a Coulomb static stress increase due to the Tohoku-oki earthquake, calculated using a variable slip model for the mainshock and regional focal mechanisms of events occurred before and after the M9.0 earthquake. The largest stress increase is of about 1.0 bar, as estimated on earthquake nodal planes of maximum stress change. The time-decay characteristics of the activated seismicity favor the triggering by static stresses. Such validations of the Coulomb hypothesis support our stress perturbation assessment on the Tokai gap. To precisely calculate the stress changes on the Tokai source, we use the curved plate interface and plate-motion inferred rake directions. The computed stress changes are predominantly positive but have relatively small values, of less than 0.1 bar. The large afterslip (Mw8.6) and the aftershocks following the Tohoku-oki earthquake caused additional, but minor, stress increases. Our results imply that the stress-state on the Tokai plane did not change significantly after the Tohoku-oki event, however static stress driven seismic activation in neighboring areas can bring a secondary impact on the interplate seismicity.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2016-04-15
    Description: We present a new approach for broadband ground-motion simulation that is a combination of high-frequency (HF, f 〉0.5 Hz) and low-frequency (LF, f 〈0.5 Hz) ground-motion simulations. In this method, the LF ground motion is first computed by a deterministic approach based on a velocity model and a source model. Then, the HF acceleration envelopes are computed by multiplying the LF envelopes by envelope ratio functions (ERFs), which are defined as the empirical relationships between the characteristics of envelopes of different frequency bands. We apply the method to the 2003 Tokachi-Oki, Japan, earthquake ( M w  8.3). The LF ground motion is computed by a finite-difference method with a 3D velocity model and a finite-fault slip model. Because of the complicated rupture process of the earthquake, the fault is divided into subfaults that can be considered as smaller earthquakes. ERFs are estimated by investigating the ground-motion data of moderate-size aftershocks (5.4≤ M w ≤6.6) for each station. The HF ground motions are simulated using the LF ground motion and the ERFs. Seismograms of all frequency bands are summed to give a time series of broadband (0.05–16 Hz) ground motion. We find that our method yields realistic broadband ground motion, in terms of the acceleration envelope, velocity waveform, and Fourier amplitude spectrum. Comparing the HF waveforms with those computed by the stochastic Green’s function method (SGFM), we find that the performance of our method is better than that of the SGFM under the condition that LF waveforms are appropriately computed. The proposed method has the potential to be used as a practical method for broadband ground-motion prediction incorporating the effects of a 3D velocity model and a finite-source model. Online Material: Figures comparing simulated and observed low-frequency waveforms and root mean square acceleration envelopes in different frequency ranges.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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  • 10
    Publication Date: 2012-09-19
    Description: Slow slip events (SSEs) are another mode of fault deformation than the fast faulting of regular earthquakes. Such transient episodes have been observed at plate boundaries in a number of subduction zones around the globe. The SSEs near the Boso Peninsula, central Japan, are among the most documented SSEs, with...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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