ISSN:
0025-116X
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
A novel polymerizable phospholipid with conjugated diene groups at the hydrocarbon chain ends, 1,2-bis(11,13-tetradecadienoyl)-sn-glycero-3-phosphocholine (7), was synthesized. This phospholipid gives liposomes which can be readily polymerized upon γ-and UV-irradiation. The conversion is up to 95% within 10 h at 60°C or within 3 days at room temperature. According to light scattering, 31P NMR and electron microscopy, the polymerized liposomes are detergent-resistent and maintain their structure under ultrasonic treatment and in organic solvent media.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/macp.1993.021941002
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