ISSN:
1432-1041
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary The effects of hyperventilation were studied in twenty hypertensive patients during oral treatment with guanethidine and in ten hypertensive patients during surgical procedures under general anaesthesia, following intravenous administration of reserpine. Hyperventilation prior to any treatment did not produce arterial pressure changes of any significance. During therapy, a depressor effect took place, which in some of the patients was markedly pronounced. Similarly, hyperventilation was studied in ten normotensive patients undergoing surgery under general anaesthesia with moderate hypothermia. We noted that during the early stages of hypothermia, hyperventilation produced a pressor effect, which in some patients was very pronounced. Contrary to this, in the late stages of hypothermia, hyperventilation did not produce any arterial pressure changes. The pressor effect observed at the beginning of hypothermia is probably related to an increased catecholamine release taking place during the early stage of induction of cooling.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00456943
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