ISSN:
1572-8927
Keywords:
α-amino acids
;
excess properties
;
chiral recognition
;
NMR relaxation times
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Calorimetric, densimetric, and nuclear relaxation time measurements were carried out at 25°C on binary and ternary aqueous solutions containing L and D forms of the following amino acids bearing substituted alkyl chains: lysine, glutamine, arginine, asparagine, serine, and homoserine. For three of them (lysine, glutamine, and arginine), very high differences were found between the values of the homochiral and heterochiral pairwise enthalpic interaction coefficients. Volume and spectroscopic data showed that it is possible to detect chiral recognition by techniques other than calorimetric. The role of the zwitterionic interaction and of the substituted side chain is discussed to explain the enhanced chiral recognition of these α-aminoacids in respect to those bearing unsubstituted alkyl chains (alanine, α-aminobutyric acid, valines and leucines).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01004479
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