ISSN:
1432-1041
Keywords:
ischaemic heart disease
;
alprenolol
;
long-term treatment
;
serum magnesium
;
serum calcium
;
parathyroid hormone
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary In 40 patients with ischaemic heart disease the serum levels of magnesium, parathyroid hormone (PTH), phosphate, calcium, and ionized calcium remained unchanged and within normal limits following treatment for 12 months with alprenolol (n=20) or placebo (n=20). No changes occurred during a 2 week withdrawal period. The clinical implication is that the non-cardioselective betablocker alprenolol can be given to patients with ischaemic heart disease without the risk of inducing potentially cardiotoxic disturbances in serum magnesium and serum calcium levels. Whether this applies to cardioselective beta-blockers remains to be established.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00540959
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