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  • 1
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    SPIDAST: a new modular software to process spectrointerferometric measurements (2013)
    Oxford University Press
    Details
    Publication Date: 2013-05-26
    Description: Extracting stellar fundamental parameters from Spectrointerferometric (SPI) data requires reliable estimates of observables and with robust uncertainties (visibility, triple product, phase closure). A number of fine calibration procedures are necessary throughout the reduction process. Testing departures from centrosymmetry of brightness distributions is a useful complement. Developing a set of automatic routines called spidast (made available to the community) to reduce, calibrate and interpret raw data sets of instantaneous spectrointerferograms at the spectral channel level, we complement (and in some respects improve) the ones contained in the amdlib Data Reduction Software. Our new software spidast is designed to work in an automatic mode, free from subjective choices, while being versatile enough to suit various processing strategies. spidast performs the following automated operations: weighting of non-aberrant SPI data (visibility, triple product), fine spectral calibration (subpixel level), accurate and robust determinations of stellar diameters for calibrator sources (and their uncertainties as well), correction for the degradations of the interferometer response in visibility and triple product, calculation of the centrosymmetry parameter from the calibrated triple product, fit of parametric chromatic models on SPI observables, to extract model parameters. spidast is currently applied to the scientific study of 18 cool giant and supergiant stars, observed with the VLTI/AMBER facility at medium resolution in the K band. Because part of their calibrators have no diameter in the current catalogues, spidast provides new determinations of the angular diameters of all calibrators. Comparison of spidast final calibrated observables with amdlib determinations shows good agreement, under good and poor seeing conditions.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 2
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    Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-04-10
    Description: Directionality in intracellular trafficking is essential to ensure the correct localization of proteins along the secretory pathway. Here, we found evidence for an active mechanism that prohibited back-fusion of de novo-generated vesicles with their donor compartment. Tip20p is a peripheral membrane protein implicated in consumption of COPI vesicles at the endoplasmic reticulum. However, a specific mutant of TIP20 did not interfere with COPII vesicle generation but allowed these vesicles to fuse back to the endoplasmic reticulum, a process that does not occur normally in the cell.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kamena, Faustin -- Spang, Anne -- New York, N.Y. -- Science. 2004 Apr 9;304(5668):286-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Friedrich Miescher Laboratorium der Max Planck Gesellschaft, Spemannstrasse 39, D-72076 Tubingen, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15073376" target="_blank"〉PubMed〈/a〉
    Keywords: COP-Coated Vesicles/*physiology/ultrastructure ; Carrier Proteins/genetics/*physiology ; Endoplasmic Reticulum/metabolism/*physiology/ultrastructure ; Glycoproteins/genetics/*physiology ; Golgi Apparatus/metabolism ; Intracellular Membranes/physiology/ultrastructure ; *Membrane Fusion ; Mutation ; Peptides/metabolism ; Protein Transport ; Recombinant Fusion Proteins/metabolism ; Saccharomyces cerevisiae/genetics/*physiology/ultrastructure ; Saccharomyces cerevisiae Proteins/genetics/metabolism ; Vesicular Transport Proteins ; alpha-Glucosidases/genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Complex archaea that bridge the gap between prokaryotes and eukaryotes (2015)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2015-05-07
    Description: The origin of the eukaryotic cell remains one of the most contentious puzzles in modern biology. Recent studies have provided support for the emergence of the eukaryotic host cell from within the archaeal domain of life, but the identity and nature of the putative archaeal ancestor remain a subject of debate. Here we describe the discovery of 'Lokiarchaeota', a novel candidate archaeal phylum, which forms a monophyletic group with eukaryotes in phylogenomic analyses, and whose genomes encode an expanded repertoire of eukaryotic signature proteins that are suggestive of sophisticated membrane remodelling capabilities. Our results provide strong support for hypotheses in which the eukaryotic host evolved from a bona fide archaeon, and demonstrate that many components that underpin eukaryote-specific features were already present in that ancestor. This provided the host with a rich genomic 'starter-kit' to support the increase in the cellular and genomic complexity that is characteristic of eukaryotes.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444528/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444528/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Spang, Anja -- Saw, Jimmy H -- Jorgensen, Steffen L -- Zaremba-Niedzwiedzka, Katarzyna -- Martijn, Joran -- Lind, Anders E -- van Eijk, Roel -- Schleper, Christa -- Guy, Lionel -- Ettema, Thijs J G -- 310039/European Research Council/International -- England -- Nature. 2015 May 14;521(7551):173-9. doi: 10.1038/nature14447. Epub 2015 May 6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-75123 Uppsala, Sweden. ; Department of Biology, Centre for Geobiology, University of Bergen, N-5020 Bergen, Norway. ; 1] Department of Biology, Centre for Geobiology, University of Bergen, N-5020 Bergen, Norway [2] Division of Archaea Biology and Ecogenomics, Department of Ecogenomics and Systems Biology, University of Vienna, A-1090 Vienna, Austria. ; 1] Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-75123 Uppsala, Sweden [2] Department of Medical Biochemistry and Microbiology, Uppsala University, SE-75123 Uppsala, Sweden.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25945739" target="_blank"〉PubMed〈/a〉
    Keywords: Actin Cytoskeleton/metabolism ; Actins/genetics/metabolism ; Archaea/*classification/genetics/metabolism ; Arctic Regions ; Endosomal Sorting Complexes Required for Transport/genetics/metabolism ; Eukaryota/*classification/genetics/metabolism ; Eukaryotic Cells/classification/metabolism ; *Evolution, Molecular ; Hydrothermal Vents/*microbiology ; Metagenome/genetics ; Molecular Sequence Data ; Monomeric GTP-Binding Proteins/genetics/metabolism ; *Phylogeny ; Prokaryotic Cells/*classification ; Proteome/genetics/isolation & purification/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 4
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    Integrative modeling of gene and genome evolution roots the archaeal tree of life [Evolution] (2017)
    National Academy of Sciences
    Details
    Publication Date: 2017-06-07
    Description: A root for the archaeal tree is essential for reconstructing the metabolism and ecology of early cells and for testing hypotheses that propose that the eukaryotic nuclear lineage originated from within the Archaea; however, published studies based on outgroup rooting disagree regarding the position of the archaeal root. Here we...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 5
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    Decompression and Fracturing Caused by Magmatically Induced Thermal Stresses (2023)
    Details
    Publication Date: 2023-09-12
    Description: Studies of host rock deformation around magmatic intrusions usually focus on the development of stresses directly related to the intrusion process. This is done either by considering an inflating region that represents the intruding body, or by considering multiphase deformation. Thermal processes, especially volume changes caused by thermal expansion are typically ignored. We show that thermal stresses around upper crustal magma bodies are likely to be significant and sufficient to create an extensive fracture network around the magma body by brittle yielding. At the same time, cooling induces decompression within the intrusion, which can promote the appearance of a volatile phase. Volatile phases and the development of a fracture network around the inclusion may thus be the processes that control magmatic‐hydrothermal alteration around intrusions. This suggests that thermal stresses likely play an important role in the development of magmatic systems. To quantify the magnitude of thermal stresses around cooling intrusions, we present a fully compressible 2D visco‐elasto‐plastic thermo‐mechanical numerical model. We utilize a finite difference staggered grid discretization and a graphics processing unit based pseudo‐transient solver. First, we present purely thermo‐elastic solutions, then we include the effects of viscous relaxation and plastic yielding. The dominant deformation mechanism in our models is determined in a self‐consistent manner, by taking into account stress, pressure, and temperature conditions. Using experimentally determined flow laws, the resulting thermal stresses can be comparable to or even exceed the confining pressure. This suggests that thermal stresses alone could result in the development of a fracture network around magmatic bodies.
    Description: Plain Language Summary: Quantifying the stresses that magma bodies exert on the surrounding rocks is an important part of understanding mechanical processes that control the evolution of magmatic systems and volcanic eruptions. Previous analytical or numerical models typically describe the mechanical response to changes in magma volume due to intrusion or extraction of magma. However, volume changes related to thermal expansion/contraction around a cooling magma body are often neglected. Here, we develop a new software which runs on modern graphics processing unit machines, to quantity the effect of this process. The results show that stresses due to thermal expansion/contraction are significant, and often large enough to fracture the rocks nearby the magma body. Such fracture networks may form permeable pathways for the magma or for fluids such as water and CO〈sub〉2〈/sub〉, thus influencing the evolution of magmatic and hydrothermal systems. Finally we show that cooling and shrinking of magma bodies causes significant decompression which can influence the chemical evolution of the magma during crystallization and devolatilization.
    Description: Key Points: We present a numerical quantification of the effect of thermal stresses in visco‐elasto‐plastic rock with tensile and dilatant shear failure. The pressure drop in thermally contracting upper crustal magma bodies can exceed 100 MPa, potentially triggering devolatilization. Thermal cracking can create an extensive fracture network around an upper crustal magma body.
    Description: European Research Council http://dx.doi.org/10.13039/501100000781
    Description: https://zenodo.org/record/6958273
    Description: https://doi.org/10.5281/zenodo.6958273
    Keywords: ddc:551.8 ; magmatic intrusions ; host rock deformation ; thermal stress ; numerical quantification
    Language: English
    Type: doc-type:article
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  • 6
    Electronic Resource
    Electronic Resource
    Evidence for distinct dibasic processing endopeptidases with Lys-Arg and Arg-Arg specificities in neurohypophysial secretory granules
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 183 (1992), S. 128-137 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(92)91618-Z
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  • 7
    Electronic Resource
    Electronic Resource
    Processing endopeptidase deficiency in neurohypohysial secretory granules of the diabetes insipidus (Brattleboro) rat (1992)
    Springer
    Bioscience reports 12 (1992), S. 445-451 
    Details
    ISSN: 1573-4935
    Keywords: Diabetes insipidus (Brattleboro) rat ; dibasic processing endopeptidases ; neurosecretory granules ; neurohypophysial hormones ; provasopressin processing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The homozygote Brattleboro rat exhibits a hereditary diabetes insipidus due to a deficiency of vasopressin, the antidiuretic hormone. It has previously been shown that in this animal a single nucleotide deletion in the provasopressin gene leads to a mutant precursor with a C-terminal amino acid sequence different from that of the wild-type. However the N-terminal region including the hormone moiety, the processing signal as well as the first two-thirds of the neurophysin is entirely preserved and absence of maturation has to be explained by an additional cause. We show here that the neurohypophysis of the homozygote Brattleboro rat, in contrast to the adenohypophysis, displays a significant decrease in the Lys-Arg processing endopeptidase activity when compared to the heterozygote or the wild-type Wistar. It is suggested that hypothalamic vasopressinergic neurons of the homozygote Brattleboro rat display a deficiency in the processing enzyme in contrast to the oxytocinergic neurons in which processing of prooxytocin is normal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01122032
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  • 8
    Electronic Resource
    Electronic Resource
    Über radiochemische Methoden zur Untersuchung von Austauschreaktionen an Niederschlagen (1962)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 188 (1962), S. 52-52 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501041
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  • 9
    Electronic Resource
    Electronic Resource
    Für die Bestimmung von Submikrogrammengen Kupfer in biologischem Material (1962)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 188 (1962), S. 219-220 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00483313
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  • 10
    Electronic Resource
    Electronic Resource
    Ein modifiziertes Verfahren zur Bestimmung von Tritium nach der Wilzbach-Methode (1962)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 188 (1962), S. 363-364 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00473245
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