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  • 1
    Publication Date: 2011-09-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Araque, Alfonso -- Navarrete, Marta -- New York, N.Y. -- Science. 2011 Sep 16;333(6049):1587-8. doi: 10.1126/science.1212525.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto Cajal, Consejo Superior de Investigaciones Cientificas, Madrid 28002, Spain. araque@cajal.csic.es〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21921188" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Adenosine Triphosphate/metabolism ; Animals ; Axons/*physiology ; Calcium Signaling ; Cells, Cultured ; Electric Stimulation ; Ganglia, Spinal/cytology ; Glutamic Acid/metabolism ; Myelin Basic Protein/*metabolism ; Myelin Sheath/*physiology ; Neural Stem Cells/cytology/metabolism ; Oligodendroglia/cytology/*metabolism ; Signal Transduction ; Synaptic Transmission ; Synaptic Vesicles/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2007-08-25
    Description: Astrocytes play active roles in brain physiology. They respond to neurotransmitters and modulate neuronal excitability and synaptic function. However, the influence of astrocytes on synaptic transmission and plasticity at the single synapse level is unknown. Ca(2+) elevation in astrocytes transiently increased the probability of transmitter release at hippocampal area CA3-CA1 synapses, without affecting the amplitude of synaptic events. This form of short-term plasticity was due to the release of glutamate from astrocytes, a process that depended on Ca(2+) and soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein and that activated metabotropic glutamate receptors (mGluRs). The transient potentiation of transmitter release became persistent when the astrocytic signal was temporally coincident with postsynaptic depolarization. This persistent plasticity was mGluR-mediated but N-methyl-d-aspartate receptor-independent. These results indicate that astrocytes are actively involved in the transfer and storage of synaptic information.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perea, Gertrudis -- Araque, Alfonso -- New York, N.Y. -- Science. 2007 Aug 24;317(5841):1083-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto Cajal, Consejo Superior de Investigaciones Cientificas, Madrid, Spain.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17717185" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Animals ; Astrocytes/*physiology ; Calcium/metabolism ; Calcium Signaling ; Excitatory Postsynaptic Potentials ; Glutamic Acid/metabolism ; Hippocampus/*cytology/physiology ; Long-Term Potentiation ; Neuronal Plasticity ; Neurotransmitter Agents/*metabolism ; Patch-Clamp Techniques ; Pyramidal Cells/*physiology ; Rats ; Rats, Wistar ; Receptors, Metabotropic Glutamate/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Synapses/*physiology ; *Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2015-08-15
    Description: Astrocytes are important regulatory elements in brain function. They respond to neurotransmitters and release gliotransmitters that modulate synaptic transmission. However, the cell- and synapse-specificity of the functional relationship between astrocytes and neurons in certain brain circuits remains unknown. In the dorsal striatum, which mainly comprises two intermingled subtypes (striatonigral and striatopallidal) of medium spiny neurons (MSNs) and synapses belonging to two neural circuits (the direct and indirect pathways of the basal ganglia), subpopulations of astrocytes selectively responded to specific MSN subtype activity. These subpopulations of astrocytes released glutamate that selectively activated N-methyl-d-aspartate receptors in homotypic, but not heterotypic, MSNs. Likewise, astrocyte subpopulations selectively regulated homotypic synapses through metabotropic glutamate receptor activation. Therefore, bidirectional astrocyte-neuron signaling selectively occurs between specific subpopulations of astrocytes, neurons, and synapses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Martin, R -- Bajo-Graneras, R -- Moratalla, R -- Perea, G -- Araque, A -- New York, N.Y. -- Science. 2015 Aug 14;349(6249):730-4. doi: 10.1126/science.aaa7945.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto Cajal, Consejo Superior de Investigaciones Cientificas, 28002 Madrid, Spain. ; Instituto Cajal, Consejo Superior de Investigaciones Cientificas, 28002 Madrid, Spain. Centro de Investigacion Biomedica en Red Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, 28029 Madrid, Spain. ; Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA. araque@umn.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26273054" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Astrocytes/*physiology ; Basal Ganglia/cytology/*physiology ; Cell Communication ; Glutamates/*metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Net/physiology ; Neurons/*physiology ; Receptors, Metabotropic Glutamate/agonists/metabolism ; Receptors, N-Methyl-D-Aspartate/agonists/metabolism ; Signal Transduction ; Synapses/*physiology ; *Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2019
    Description: Consumer preferences in sustaining and designing a product are a vital driver in a company’s long-term strategy. In a supply chain management (SCM), realizing, configuring and analyzing consumer point of view and making sure the product is highly fitted to the consumer dimensions are essential responsibilities. For this purpose, a sustainable supply chain (SSC) can define a platform in order to reach consumer satisfaction. This paper examines the utility and factors related to the use of a phone in the market incorporating sustainable attributes. We firstly identify main factors and indicators that influence the selection of a sustainable phone. Thereafter, we propose decision analysis tools as decision-making trial and evaluation laboratory (DEMATEL) and analytical hierarchy process (AHP) for the realization of the cause, effect, and interrelation of the indicators. The comparisons between them report a high similarity while best and worst indicators are in the same positions. Best worst method (BWM) is then formulated in order to achieve optimal ranking and to express the importance. Counting on this information is of special relevance in marketing decision-making, where companies must look for competitive advantages prioritizing its product attributes, attending both to resources and to consumer preferences. For this project, we invited six experts in various areas (information science, consumer organizations, fair trade, public administration-cooperation office and telecommunication) to participate and fill the questionnaires. The results are analyzed by market experts in terms of comparison and conformity.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by MDPI
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  • 5
    Publication Date: 1994-05-10
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 6
    Publication Date: 2015-08-14
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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