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  • 1
    Keywords: Immunospecificity. ; Biology Technique. ; Immunology. ; Biotechnology. ; Adaptive Immunity. ; Biological Techniques. ; Immunology. ; Biotechnology.
    Description / Table of Contents: History of IgY-Technology -- Characteristics of IgY antibody -- Chicken keeping -- Basics of egg laying processes -- IgY extraction from yolk -- Immunization of chickens -- Cost calculation of industrial production of IgY preparations -- Application of IgY.– Human Medicine -- Application of IgY.– Veterinary Medicine -- Use of IgY Ab in aquaculture -- Molecularbiological methods for IgY-Ab production -- IgY receptors -- Additional aspects of IgY-technology.
    Abstract: This first edited Volume on IgY-Technology, addresses the historical and dynamic development of IgY-applications. The authors cover the biological basis and theoretical context, methodological guidance, and applications of IgY-Technology. A focus is laid on the use of IgY-antibodies for prophylactic/therapeutic purposes in human and veterinary medicine. Aside from applications, the chapters also offer an evolutionary understanding of the IgY molecule, IgY receptors and practical prerequisites to produce IgY-antibodies. Guidance is given for every step of the process. Starting with an introduction to hens as a model species and including hen husbandry, hen egg-laying capacity and total IgY outcomes. Readers will also learn about immunization techniques, the advantages and limitations of different IgY extraction methods, as well as storage stability of the final product. The last part of the volume highlights hands-on aspects of applications, such as IgY delivery strategies, new methods to produce monoclonal IgY-antibodies or production of functional IgY fragments by phage-display as well as commercial exploitation of the technology. Thus, this book is a valuable resource and guide for Scientists, Clinicians and Health Product Developers in both human and veterinary medicine.
    Type of Medium: Online Resource
    Pages: XV, 313 p. 48 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030726881
    DDC: 571.9646
    Language: English
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  • 2
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    Berlin [u.a.] : Springer [u.a.]
    Call number: M 01.0478/1+2
    Series Statement: Springer series in surface sciencesy
    Classification:
    E.3.
    Language: English
    Branch Library: GFZ Library
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  • 3
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    PANGAEA
    In:  Supplement to: Mohtadi, Mahyar; Prange, Matthias; Oppo, Delia W; De Pol-Holz, Ricardo; Merkel, Ute; Zhang, Xiao; Steinke, Stephan; Lückge, Andreas (2014): North Atlantic forcing of tropical Indian Ocean climate. Nature, 509(7498), 76-80, https://doi.org/10.1038/nature13196
    Publication Date: 2023-03-03
    Description: The response of the tropical climate in the Indian Ocean realm to abrupt climate change events in the North Atlantic Ocean is contentious. Repositioning of the intertropical convergence zone is thought to have been responsible for changes in tropical hydroclimate during North Atlantic cold spells1, 2, 3, 4, 5, but the dearth of high-resolution records outside the monsoon realm in the Indian Ocean precludes a full understanding of this remote relationship and its underlying mechanisms. Here we show that slowdowns of the Atlantic meridional overturning circulation during Heinrich stadials and the Younger Dryas stadial affected the tropical Indian Ocean hydroclimate through changes to the Hadley circulation including a southward shift in the rising branch (the intertropical convergence zone) and an overall weakening over the southern Indian Ocean. Our results are based on new, high-resolution sea surface temperature and seawater oxygen isotope records of well-dated sedimentary archives from the tropical eastern Indian Ocean for the past 45,000 years, combined with climate model simulations of Atlantic circulation slowdown under Marine Isotope Stages 2 and 3 boundary conditions. Similar conditions in the east and west of the basin rule out a zonal dipole structure as the dominant forcing of the tropical Indian Ocean hydroclimate of millennial-scale events. Results from our simulations and proxy data suggest dry conditions in the northern Indian Ocean realm and wet and warm conditions in the southern realm during North Atlantic cold spells.
    Keywords: Center for Marine Environmental Sciences; MARUM
    Type: Dataset
    Format: application/zip, 4 datasets
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  • 4
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    PANGAEA
    In:  Supplement to: Handiani, Dian Noor; Paul, André; Prange, Matthias; Merkel, Ute; Dupont, Lydie M; Zhang, Xiao (2013): Tropical vegetation response to Heinrich Event 1 as simulated with the UVic ESCM and CCSM3. Climate of the Past, 9(4), 1683-1696, https://doi.org/10.5194/cp-9-1683-2013
    Publication Date: 2023-01-13
    Description: We investigated changes in tropical climate and vegetation cover associated with abrupt climate change during Heinrich Event 1 (HE1, ca. 17.5 ka BP) using two different global climate models: the University of Victoria Earth System-Climate Model (UVic ESCM) and the Community Climate System Model version 3 (CCSM3). Tropical South American and African pollen records suggest that the cooling of the North Atlantic Ocean during HE1 influenced the tropics through a southward shift of the rain belt. In this study, we simulated the HE1 by applying a freshwater perturbation to the North Atlantic Ocean. The resulting slowdown of the Atlantic Meridional Overturning Circulation was followed by a temperature seesaw between the Northern and Southern Hemispheres, as well as a southward shift of the tropical rain belt. The shift and the response pattern of the tropical vegetation around the Atlantic Ocean were more pronounced in the CCSM3 than in the UVic ESCM simulation. For tropical South America, opposite changes in tree and grass cover were modeled around 10° S in the CCSM3 but not in the UVic ESCM. In tropical Africa, the grass cover increased and the tree cover decreased around 15° N in the UVic ESCM and around 10° N in the CCSM3. In the CCSM3 model, the tree and grass cover in tropical Southeast Asia responded to the abrupt climate change during the HE1, which could not be found in the UVic ESCM. The biome distributions derived from both models corroborate findings from pollen records in southwestern and equatorial western Africa as well as northeastern Brazil.
    Keywords: Description; File name; File size; File type; Uniform resource locator/link to model result file
    Type: Dataset
    Format: text/tab-separated-values, 90 data points
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  • 5
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    PANGAEA
    In:  Supplement to: Zhang, Xiao; Prange, Matthias; Steph, Silke; Butzin, Martin; Krebs, Uta; Lunt, Daniel J; Nisancioglu, Kerim H; Park, Wonsun; Schmittner, Andreas; Schneider, Birgit; Schulz, Michael (2012): Changes in equatorial Pacific thermocline depth in response to Panamanian seaway closure: Insights from a multi-model study. Earth and Planetary Science Letters, 317-318, 76-84, https://doi.org/10.1016/j.epsl.2011.11.028
    Publication Date: 2023-05-25
    Description: The early Pliocene warm phase was characterized by high sea surface temperatures and a deep thermocline in the eastern equatorial Pacific. A new hypothesis suggests that the progressive closure of the Panamanian seaway contributed substantially to the termination of this zonally symmetric state in the equatorial Pacific. According to this hypothesis, intensification of the Atlantic meridional overturning circulation (AMOC) - induced by the closure of the gateway - was the principal cause of equatorial Pacific thermocline shoaling during the Pliocene. In this study, twelve Panama seaway sensitivity experiments from eight ocean/climate models of different complexity are analyzed to examine the effect of an open gateway on AMOC strength and thermocline depth. All models show an eastward Panamanian net throughflow, leading to a reduction in AMOC strength compared to the corresponding closed-Panama case. In those models that do not include a dynamic atmosphere, deepening of the equatorial Pacific thermocline appears to scale almost linearly with the throughflow-induced reduction in AMOC strength. Models with dynamic atmosphere do not follow this simple relation. There are indications that in four out of five models equatorial wind-stress anomalies amplify the tropical Pacific thermocline deepening. In summary, the models provide strong support for the hypothesized relationship between Panama closure and equatorial Pacific thermocline shoaling.
    Keywords: File content; File format; File name; File size; Uniform resource locator/link to file
    Type: Dataset
    Format: text/tab-separated-values, 30 data points
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  • 6
    Publication Date: 2023-06-08
    Description: As a supplementary or sometimes the only water source in dry regions, dew plays a critical role in the survival of organisms in such environments. The new hydrological tracer 17O-excess, with almost sole dependence on relative humidity, provides a new way to distinguish the evaporation processes and reconstruct the paleoclimate. Up to now, there is no daily dew isotope record on δ2H, δ18O, δ17O, d-excess, and 17O-excess. To fill this gap, here we collected daily dew (n=114) between July 2014 and April 2018 from three distinct climatic regions (i.e., Gobabeb-Namib Research Institute in the central Namib Desert with desert climate, Nice in France with Mediterranean climate, and Indianapolis in the central United States with humid continental climate). The isotopic composition (δ2H, δ18O, and δ17O) of dew was simultaneously analyzed using a Triple Water Vapor Isotope Analyzer (T-WVIA) based on Off-Axis Integrated Cavity Output Spectroscopy (OA-ICOS) technique, and then d-excess and 17O-excess were calculated. The latitude, longitude, and elevation as well as three meteorological factors including temperature, relative humidity (RH), and vapour-pressure deficit (VPD) of the three collection sites were also provided here. This report presents daily dew isotope dataset under three different climatic regions. It is useful for researchers to use it as a data reference when studying global dew dynamics and dew formation mechanisms.
    Keywords: Calculated; DATE/TIME; Deuterium excess; DewIsotope_Gobabeb; DewIsotope_Indianapolis; DewIsotope_Nice; ELEVATION; Event label; Gobabeb; Humidity, relative; Indianapolis; LATITUDE; LONGITUDE; Nice; Oxygen-17 excess; Site; Temperature, air; Triple water vapor Isotope analyzer (T-WVIA) based on off-axis integrated cavity output spectroscopy (OA-ICOS); Vapour pressure deficit; δ17O; δ18O; δ Deuterium
    Type: Dataset
    Format: text/tab-separated-values, 1020 data points
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  • 7
    Publication Date: 2023-06-27
    Keywords: AGE; Center for Marine Environmental Sciences; Globigerinoides ruber sensu stricto, δ18O; Indian Ocean; KL; MARUM; Mass spectrometer Finnigan MAT 251; Piston corer (BGR type); SO189/2; SO189/2_144KL; Sonne; SUMATRA
    Type: Dataset
    Format: text/tab-separated-values, 379 data points
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  • 8
    Publication Date: 2023-06-27
    Keywords: Age, 14C AMS; Age, 14C calibrated, CALIB 7.0 with MARINE13 calibration curve (Reimer et al. 2013); Age, dated; Age, dated material; Age, dated standard deviation; Calendar age; Calendar age, standard deviation; Center for Marine Environmental Sciences; DEPTH, sediment/rock; Event label; Indian Ocean; KL; MARUM; Piston corer (BGR type); Sample code/label; SO189/2; SO189/2_039KL; SO189/2_119KL; SO189/2_144KL; Sonne; SUMATRA
    Type: Dataset
    Format: text/tab-separated-values, 1134 data points
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  • 9
    Publication Date: 2023-12-05
    Keywords: AGE; Calculated from Mg/Ca ratios (Anand et al., 2003); Center for Marine Environmental Sciences; Globigerinoides ruber sensu stricto, δ18O; Indian Ocean; KL; MARUM; Mass spectrometer Finnigan MAT 251; Piston corer (BGR type); Sea surface temperature, annual mean; SO189/2; SO189/2_119KL; Sonne; SUMATRA; δ18O, water
    Type: Dataset
    Format: text/tab-separated-values, 406 data points
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  • 10
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    PANGAEA
    In:  Supplement to: Zhang, Yancheng; Zhang, Xu; Chiessi, Cristiano Mazur; Mulitza, Stefan; Zhang, Xiao; Lohmann, Gerrit; Prange, Matthias; Behling, Hermann; Zabel, Matthias; Govin, Aline; Sawakuchi, André Oliveira; da Cruz Junior, Francisco William; Wefer, Gerold (2016): Equatorial Pacific forcing of western Amazonian precipitation during Heinrich Stadial 1. Scientific Reports, 6, 35866, https://doi.org/10.1038/srep35866
    Publication Date: 2023-11-25
    Description: Abundant hydroclimatic evidence from western Amazonia and the adjacent Andes documents wet conditions during Heinrich Stadial 1 (HS1, 18-15 ka), a cold period in the high latitudes of the North Atlantic. This precipitation anomaly was attributed to a strengthening of the South American summer monsoon due to a change in the Atlantic interhemispheric sea surface temperature (SST) gradient. However, the physical viability of this mechanism has never been rigorously tested. We address this issue by combining a thorough compilation of tropical South American paleorecords and a set of atmosphere model sensitivity experiments. Our results show that the Atlantic SST variations alone, although leading to dry conditions in northern South America and wet conditions in northeastern Brazil, cannot produce increased precipitation over western Amazonia and the adjacent Andes during HS1. Instead, an eastern equatorial Pacific SST increase (i.e., 0.5-1.5 °C), in response to the slowdown of the Atlantic Meridional Overturning Circulation during HS1, is crucial to generate the wet conditions in these regions. The mechanism works via anomalous low sea level pressure over the eastern equatorial Pacific, which promotes a regional easterly low-level wind anomaly and moisture recycling from central Amazonia towards the Andes.
    Keywords: 202-1240; 202-1242; CD38-17P; Center for Marine Environmental Sciences; Cocos Ridge; Comment; COMPCORE; Composite Core; Difference; Equatorial East Pacific; Event label; GC; Giant piston corer; GPC; Gravity corer; IMAGES VIII - MONA; Joides Resolution; KNR195-5-CDH26; Leg202; Marion Dufresne (1995); MARUM; MD022529; MD02-2529; MD126; ME0005A; ME0005A-27JC; ME0005A-43JC; Melville; NEMO; North Pacific Ocean; PC; Piston corer; Reference/source; Sample code/label; Sea surface temperature; South Pacific Ocean; Species; TR163-19; TR163-22; V19; V19-27; V19-28; V19-30; V21; V21-30; Vema
    Type: Dataset
    Format: text/tab-separated-values, 88 data points
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