Publication Date:
2016-02-26
Description:
Three new atisane diterpenoids, spiratisanins A – C ( 1 – 3 , resp.), featuring a phenylacryloxyl substituted ent -atisane skeleton, were isolated from Spiraea japonica together with two known atisine diterpene alkaloids, spiramine A ( 4 ) and spiradine F ( 5 ). The structures of the new compounds were elucidated as (5 β ,7 α ,8 α ,9 β ,10 α ,12 α ,16 β )-16-hydroxyatisan-7-yl (2 E )-3-phenylprop-2-enoate ( 1 ), (5 β ,7 α ,8 α ,9 β ,10 α ,12 α )-16-hydroxyatisan-7-yl (2 E )-3-phenylprop-2-enoate ( 2 ), and (5 β ,8 α ,9 β ,10 α ,12 α ,16 β )-16-hydroxyatisan-20-yl (2 E )-3-phenylprop-2-enoate ( 3 ) on the basis of spectroscopic analysis. This article is protected by copyright. All rights reserved.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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