ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A 300 base pair deletion near the 3′-end of the gene encoding Type II (cartilage) collagen has been implicated in the pathogenesis of perinatal lethal osteogenesis imperfecta. We have found similar deletions occurring at a high frequency in normal Asian Indian and West Indian populations generated by a length polymorphism just beyond the 3′-end of the gene. We suggest that this polymorphism provides an alternative explanation of the original results.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00389455
Permalink