ISSN:
1546-1696
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
[Auszug] Genome editing driven by zinc-finger nucleases (ZFNs) yields high gene-modification efficiencies (〉10%) by introducing a recombinogenic double-strand break into the targeted gene. The cleavage event is induced using two custom-designed ZFNs that heterodimerize upon binding DNA to form a ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/nbt1319
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