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  • 1
    Electronic Resource
    Electronic Resource
    Effect of glucose on glutamate dehydrogenase and acid phosphatase and its reversal by cyclic adenosine 3′:5′-monophosphate in single cell cultures of Asparagus officinalis (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 60 (1984), S. 0 
    Details
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Cell cultures of Asparagus officinalis L. ev. “Argenteuil” were used to study the effect of glucose on the synthesis of glutamate dehydrogenase and acid phosphatase. Both the enzymes are progressively repressed by increasing the glucose concentration in the culture medium. Furthermore, synthesis of glutamatc dehydrogenase and acid phosphatase in cells grown in the presence of high glucose concentrations is derepressed by the addition of the cyclic adenosine 3′:5′-monophosphate to the culture medium. These data support the hypothesis that also in cells from higher plants a regulatory mechanism exists with some similarities to the “catabolite repression” mechanism operating in several prokaryotes and lower eukaryotes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3054.1984.tb04250.x
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  • 2
    Electronic Resource
    Electronic Resource
    The respiratory activities of four Hansenula species (1986)
    Springer
    Antonie van Leeuwenhoek 52 (1986), S. 295-308 
    Details
    ISSN: 1572-9699
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The respiratory activities and the cytochrome spectra from four species belonging to the genus Hansenula have been analysed. The results obtained and described in this paper show that (1) H. glucozyma posseses only the primary, antimycin A-sensitive respiration, (2) H. anomala and H. californica possess primary and secondary (salicylhydroxamate-sensitive) respirations, whereas (3) H. saturnus possesses three respiratory activities (AA-sensitive, SHAM-sensitive, and AA + SHAM-insensitive). The respiratory activity of H. glucozyma is glucose-repressible, whereas the activities of the other species are not. In addition, antimycin A (AA) and erythromycin (ERY) in the culture media differently inhibit the growth of the four species and regulate the respiratory pathways in the species analysed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00428641
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  • 3
    Electronic Resource
    Electronic Resource
    Erythromycin inhibition of sporulation inSaccharomyces cerevisiae (1971)
    Springer
    Cellular and molecular life sciences 27 (1971), S. 963-964 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Numerosi agenti chimici o condizioni fisiologiche ledono la funzionalità mitocondriale e contemporaneamente il processo di sporificazione nel lievitoSaccharomyces cerevisiae. L'antibiotico eritromicina inibisce il processo di sporificazione nel lievito normale, ma é inattivo sulla sporificazione di mutanti Eritromicina resistenti. Ció suggerisce che la sintesi proteica mitocondriale svolge un ruolo rilevante nel processo di sporificazione.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02135775
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  • 4
    Electronic Resource
    Electronic Resource
    Heterozygous effects on cell yield and generation time inSaccharomyces cerevisiae (1976)
    Springer
    Cellular and molecular life sciences 32 (1976), S. 1526-1527 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The data obtained analyzing generation time, cell yield and their variability in different culture media in diploid strains ofSaccharomyces cerevisiae demonstrate the existence of a biochemically determined heterotic effect, that could be of some relevance for the study of yeast population genetics, as well as for the improvement of microbial fermentation processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01924431
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  • 5
    Electronic Resource
    Electronic Resource
    The in vivo effect of acriflavine on mitochondrial functions in the petite negative yeast Hansenula saturnus (1986)
    Springer
    Current genetics 11 (1986), S. 127-129 
    Details
    ISSN: 1432-0983
    Keywords: Mitochondrial DNA ; Petite negative yeast ; Hansenula saturnus ; Acriflavine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In the petite negative yeast Hansenula saturnus, acriflavine determined a decrease of cell yield and of the total QO2,the disappearance of the cytochromes aa 3 and b and the inhibition of in vivo mitochondrial protein synthesis without affecting the cell survival. The restriction enzymes analysis of mitDNA shows that no specific fragmentation occurred after acriflavine treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00378204
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  • 6
    Electronic Resource
    Electronic Resource
    ALG/alg: a single gene controlling the utilization of lactate in the presence of antimycin in the yeast Saccharomyces cerevisiae (1984)
    Springer
    Current genetics 8 (1984), S. 407-411 
    Details
    ISSN: 1432-0983
    Keywords: Regulation ; Lactate utilization ; Mitochondria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A strain dependent growth on lactate in the presence of antimycin A (AA) has been observed — the strain D261 can grow on lactate and AA, whereas in the strain K8/6C antimycin A prevents the utilization of lactate and the induction of LDH. Genetic analysis demonstrates that growth on lactate in the presence of AA segregates from D261 as a single nuclear factor which we indicate by ALG1 and alg1 in its dominant and recessive states. alg1 complements the gene(s) which give(s) rise to the same phenotype in K8/6C. The analysis of the regulation by lactate of LDH in the absence and presence of AA and in rho − cells shows that growth on lactate and antimycin A is not corretated with the induction by lactate of LDH.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433906
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  • 7
    Electronic Resource
    Electronic Resource
    Analysis of rho mutability in Saccharomyces cerevisiae (1980)
    Springer
    Molecular genetics and genomics 177 (1980), S. 589-595 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The Erythromycin induced mutability of the cytoplasmic factor rho in S. cerevisiae does not depend only on the participation of its mitochondrial target (formally a mitochondrial protein synthesis component) to the replication of the mitochondrial DNA. The relative increase from the spontaneous background in the percentage of RD mutants accumulated in the presence of the drug is the same in mmc and MMC strains whereas the total number of RD mutants accumulated is about tenfold higher in mmc strains. Mutations at the mitochondrial locus that controls the sensitivity to Erythromycin reduce both the Erythromycin induced and the spontaneous mutability of rho in mmc strains indicating that the gene products of nuclear (MMC) and mitochondrial (ERYs) determinants interact in determining the fidelity of a “replicative complex” for the mitochondrial DNA. The fact that ERYR allelesaare able to suppress the pet-ts associated mutability of rho but not the RD conditional trait of these mutants makes evident that the pet-ts gene-products have an additional role beside the enzymatic or the biosynthetic ones. Since the pet-ts genes are not directly involved in the metabolism of mitochondrial DNA we hypothesize that they provide for some structures that contribute to ensure the proper conformation of a “replicative complex” for mitochondrial DNA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272668
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  • 8
    Electronic Resource
    Electronic Resource
    Analysis of rho mutability in Saccharomyces cerevisiae (1980)
    Springer
    Molecular genetics and genomics 177 (1980), S. 581-588 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Two additional types of nuclear determinants involved in the control of spontaneous mutability of rho in S. cerevisiae have been identified: mmc and the pet-ts 1, 2, 10, 52 and 53 genes. These genes in their mutated recessive form increase at various extents the number of respiratory deficient cytoplasmic “petite” mutants accumulated. The gene mmc does not affect the respiratory activity and is not temperature-dependent whereas the pet-ts genes determine at the non permissive temperature a respiratory deficient phenotypes even if they affect the mutability of rho at the permissve and at the non permissive temperature. The data here reported suggest that a “replicative complex” exists for the mitochondrial DNA. It is in the purpose of this paper to deal with the relative contrition that mmc and pet-ts gene products have in ensuring the fidelity of this “replicative complex”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272667
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  • 9
    Electronic Resource
    Electronic Resource
    Antimutagenic activity of actinomycin D and basic fuchsine in Saccharomyces cerevisiae (1968)
    Springer
    Molecular genetics and genomics 103 (1968), S. 248-252 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The antimutagenic activity, i.e. the capacity to decrease the spontaneous mutation rate, of actinomycin and basic fuchsine was investigated. It was found that the minimal requirement for the antimutagenic activity of compounds forming complexes with DNA is their binding to the polynucleotides rather than their stabilizing them against thermal denaturation. It is proposed that these antimutagens act through an inhibition of the exonucleolytic removal of bases from DNA during transcription.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273695
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  • 10
    Electronic Resource
    Electronic Resource
    Role of the mitochondrion in the regulation of protein synthesis in the eucaryote Saccharomyces cerevisiae (1971)
    Springer
    Molecular genetics and genomics 110 (1971), S. 110-117 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Induction of several enzymes is abolished in respiratory deficient strains of Saccharomyces cerevisiae. Such block depends on the integrity of the mitochondrial protein sinthesizing machinery. A model is proposed which is based on a double control of protein synthesis, a negative regulation similar to that described in E. coli and a positive regulation mediated by mitochondria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00332642
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