ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Irazepine [ 1 - (2-isothiocyanatoethyl) -7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-l,4-benzodiazepine-2-one] (Fig. la) was prepared as follows. A mixture of 203 mg (0.5 mmol) of Ro7-1986/l (Fig. Ib), 10ml of H2O, 25ml of CHC13 and 252 mg (3 mmol) of NaHCO3 was stirred vigorously for 10 min, and ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/278854a0
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