Publication Date:
2014-11-01
Description:
Article While several human papilloma virus (HPV) vaccines exist, a highly effective vaccine that mediates regression of HPV-induced tumours is lacking. Here the authors show that a therapeutic DNA vaccine-induced HPV-specific polyfunctional CD8 T cell in 7 out of 9 patients who all exhibited complete regression of lesions and viral clearance. Nature Communications doi: 10.1038/ncomms6317 Authors: Tae Jin Kim, Hyun-Tak Jin, Soo-Young Hur, Hyun Gul Yang, Yong Bok Seo, Sung Ran Hong, Chang-Woo Lee, Suhyeon Kim, Jung-Won Woo, Ki Seok Park, Youn-Young Hwang, Jaehan Park, In-Ho Lee, Kyung-Taek Lim, Ki-Heon Lee, Mi Seon Jeong, Charles D. Surh, You Suk Suh, Jong Sup Park, Young Chul Sung
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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