ISSN:
1420-9071
Keywords:
5-Azacytosine
;
5-azacytidine
;
rat pancreatitis
;
gastric secretion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary 5-Azacytosine, 1-methyl-5-azacytosine and 5-azacytidine administered to rats with a ligated pylorus block gastric secretion, gastric acidity, the extent of hemorrhage and the number and size of gastric defects. The same drugs also depress the development of experimental acute pancreatitis mediated in rats by interstitial administration of 7.5% natrium cholate into the pancreas in vivo. The drugs affected the amount of abdominal fluid and 6 h after the treatment the pathological changes were significantly decreased.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01975880
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