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  • 1
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    Diversity of G proteins in signal transduction (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-05-10
    Description: The heterotrimeric guanine nucleotide-binding proteins (G proteins) act as switches that regulate information processing circuits connecting cell surface receptors to a variety of effectors. The G proteins are present in all eukaryotic cells, and they control metabolic, humoral, neural, and developmental functions. More than a hundred different kinds of receptors and many different effectors have been described. The G proteins that coordinate receptor-effector activity are derived from a large gene family. At present, the family is known to contain at least sixteen different genes that encode the alpha subunit of the heterotrimer, four that encode beta subunits, and multiple genes encoding gamma subunits. Specific transient interactions between these components generate the pathways that modulate cellular responses to complex chemical signals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simon, M I -- Strathmann, M P -- Gautam, N -- New York, N.Y. -- Science. 1991 May 10;252(5007):802-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology, California Institute of Technology, Pasadena 91125.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1902986" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Cell Differentiation/physiology ; Chromosome Mapping ; GTP-Binding Proteins/*chemistry ; Gene Expression Regulation ; Molecular Sequence Data ; Signal Transduction/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    A G protein gamma subunit shares homology with ras proteins (1989)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1989-05-26
    Description: Guanine nucleotide binding proteins (G proteins) that transduce signals from cell surface receptors to effector molecules are made up of three subunits, alpha, beta, and gamma. A complementary DNA clone that encodes a 71-amino acid protein was isolated from bovine brain; this protein contains peptide sequences that were derived from the purified gamma subunit of Gi and Go. The primary sequence of this G protein gamma subunit (G gamma) has 55 percent homology to the gamma subunit of transducin (T gamma) and also has homology to functional domains of mammalian ras proteins. The probe for isolating the clone was generated with the use of the polymerase chain reaction (PCR). The extent of divergence between T gamma and G gamma, the isolation of homologous PCR-generated fragments, and the differences between the predicted amino acid sequence of G gamma and that derived from the gamma subunit of Gi and Go indicate that gamma subunits are encoded by a family of genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gautam, N -- Baetscher, M -- Aebersold, R -- Simon, M I -- New York, N.Y. -- Science. 1989 May 26;244(4907):971-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology, California Institute of Technology, Pasadena 91125.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2499046" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Brain Chemistry ; Cattle ; Chromatography, High Pressure Liquid ; Cloning, Molecular ; DNA-Directed DNA Polymerase ; Electrophoresis, Polyacrylamide Gel ; GTP-Binding Proteins/*genetics/isolation & purification ; Gene Amplification ; Mice ; Molecular Sequence Data ; Nucleic Acid Hybridization ; Proto-Oncogene Proteins/*genetics ; Proto-Oncogene Proteins p21(ras) ; RNA, Messenger/analysis ; Sequence Homology, Nucleic Acid
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
    Electronic Resource
    Electronic Resource
    Proper processing of a G protein γ subunit depends on complex formation with a β subunit
    Amsterdam : Elsevier
    FEBS Letters 328 (1993), S. 89-93 
    Details
    ISSN: 0014-5793
    Keywords: G protein ; βγ complex formation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(93)80971-V
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  • 4
    Electronic Resource
    Electronic Resource
    Coda Q Estimates in the Koyna Region, India (1998)
    Springer
    Pure and applied geophysics 153 (1998), S. 713-731 
    Details
    ISSN: 1420-9136
    Keywords: Key words: Qc , coda waves, Koyna region, single backscattering and lapse time window.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —The coda Q, Q c  , have been estimated for the Koyna region of India. The coda waves of 76 seismograms from thirteen local earthquakes, recorded digitally in the region during July–August, 1996, have been analyzed for this purpose at nine central frequencies viz., 1.5, 2.0, 3.0, 4.0, 6.0, 8.0, 12.0, 16.0 and 24.0 Hz using a single backscattering model. All events with magnitude less than 3 fall in the epicentral distances less than 60 km and have focal depths which range from 0.86 to 9.43 km. For the 30 sec coda window length the estimated Q c values vary from 81 to 261 at 1.5 Hz and 2088 to 3234 at 24 Hz, whereas the mean values of Q c with the standard error vary from 148 ± 13.5 at 1.5 Hz to 2703 ± 38.8 at 24 Hz. Both the estimated Q c values and their mean values exhibit the clear dependence on frequency in the region and a frequency dependence average attenuation relationship, Q c = 96f 1.09, has been obtained for the region, covering an approximate area of 11500 km2 with the surfacial extent of about 120 km and depth of 60 km.¶Lapse time dependence of Q c has also been studied for the region, with the coda waves analyzed at five lapse time windows from 20 to 60 sec duration with the difference of 10 sec. The frequency dependence average Q c relationships obtained at these window lengths Q c = 66f 1.16 (20 sec), Q c = 96f 1.09 (30 sec), Q c =131f 1.04 (40 sec), Q c = 148f 1.04 (50 sec), Q c = 182f 1.02 (60 sec) show that the frequency dependence (exponentn) remains mostly stationary at all the lapse time window lengths, while the change in Q 0 value is significant. Lapse time dependence of Q c in the region is also interpreted as the function of depth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000240050216
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  • 5
    Electronic Resource
    Electronic Resource
    Applications of SMP Bounds to Multi-class Traffic in High-speed Networks (2000)
    Springer
    Queueing systems 36 (2000), S. 351-379 
    Details
    ISSN: 1572-9443
    Keywords: Quality of Service ; admission control ; multi-class traffic ; timed round robin policy ; static priority service policy ; fluid-flow models ; fluid queues
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In this paper, we consider the stochastic fluid-flow model of a single node in a high-speed telecommunication network handling multi-class traffic. The node has multiple buffers, one for each class of traffic. The contents of these buffers are multiplexed onto a single output channel using one of the service scheduling policies: the Timed Round Robin Policy or the Static Priority Service Policy. The Quality of Service requirements for each class are based on cell loss probabilities. Using effective bandwidth methodologies and the recently developed bounds for semi-Markov modulated traffic, we solve call admission control problems for the two service scheduling policies at this node. We compare the performance of the effective bandwidth methodologies and the SMP bounds technique. We also numerically compare the performance of the two service scheduling policies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1011089403694
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  • 6
    Electronic Resource
    Electronic Resource
    Admission control of multi-class traffic with service priorities in high-speed networks (1997)
    Springer
    Queueing systems 27 (1997), S. 79-97 
    Details
    ISSN: 1572-9443
    Keywords: quality-of-service ; fluid-flow models ; effective bandwidth ; multi-priority traffic ; Chernoff dominant eigenvalue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract We consider a fluid model of a system that handles multiple classes of traffic. The delay and cell-loss requirements of the different classes of traffic are generally widely different and are achieved by assigning different buffers for different classes, and serving them in a strict priority order. We use results from the effective bandwidth of the output processes (see Chang and Thomas (1995)) to derive simple and asymptotically exact call-admission policies for such a system to guarantee the cell-loss requirements for the different classes assuming that each source produces a single class traffic. We compare the admission-control policies developed here with the approximate policy studied by Elwalid and Mitra (1995) for the case of two-class traffic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1019153812927
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  • 7
    Electronic Resource
    Electronic Resource
    The validity of equations of complex algebras (1957)
    Springer
    Archive for mathematical logic 3 (1957), S. 117-124 
    Details
    ISSN: 1432-0665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01988052
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  • 8
    Electronic Resource
    Electronic Resource
    Erratum (1962)
    Springer
    Archive for mathematical logic 6 (1962), S. 64-64 
    Details
    ISSN: 1432-0665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02025807
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  • 9
    Electronic Resource
    Electronic Resource
    Surface-level moisture transport over the Indian Ocean during southwest monsoon months using NOAA/HIRS data (1994)
    Springer
    Boundary layer meteorology 69 (1994), S. 159-171 
    Details
    ISSN: 1573-1472
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Surface-level moisture transport over the Indian Ocean has been computed using NOAA/HIRS data for the years 1980, 1981 and 1984. The global relation between monthly mean surface-level humidity and precipitable water (Liu, 1986) has been applied for the computation of surface-level humidity using monthly mean satellite-derived water vapour. The monthly mean surface wind fields over the Indian ocean provided by Florida State University have been used for the surface-level moisture flux computations. Our analysis indicates net positive surface-level moisture flux divergence over the Arabian Sea and negative moisture flux divergence over the Bay of Bengal. It has also been found that evaporation over the Arabian Sea is a variable quantity and forms a significant part of the net moisture budget over the Arabian Sea. The relative contribution of cross-equatorial flux and evaporation from the Arabian Sea has been studied for all three years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00713301
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  • 10
    Electronic Resource
    Electronic Resource
    A curiosity regarding the relation between surface level humidity and precipitable water (1992)
    Springer
    Boundary layer meteorology 60 (1992), S. 179-184 
    Details
    ISSN: 1573-1472
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract We have examined the global relation betwen the mean monthly surface level humidity and the precipitable water (Q-W relation) developed by Liu (1986) for its applicability to instantaneous data sets as proposed by Hsu and Blanchard (1989) over the Indian oceanic region. Our analysis using regional instantaneous values of W from Monex-79 in-situ data sets gave an rms error of 5.66gm/kg. This is considerably larger than the rms error of 0.4 gm/kg as obtained by Liu using the global mean monthly relation, thus failing to support Hsu and Blanchard's conjecture. However, a fifth-order polynomial in W derived by us based on instantaneous data indicates an rms error of 0.92 gm/kg.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00122067
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