ISSN:
1432-1017
Keywords:
Key words Membrane structure
;
X-ray diffraction
;
Antibiotic peptides
;
Lipid-peptide interaction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract We present the first study of grazing incidence X-ray diffraction on a model system of phospholipid membranes and antimicrobial peptides. For this purpose, highly oriented multilamellar samples have been prepared on solid substrates. By this technique, the short-range order of the lipid chains in the fluid Lα phase can be investigated quantitatively, including not only the mean distance between acyl chains, but also the associated correlation length. The short-range order in lecithin is found to be severely affected by the amphiphilic peptide magainin 2.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002490050008
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