ISSN:
1420-9071
Keywords:
Triiodothyronine
;
GH3 cells
;
membrane potential
;
membrane resistance
;
action potentials
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Electrophysiological experiments demonstrate that triiodothyronine (T3) exerts a direct effect on the membrane of a strain of cultured rat pituitary tumor cells, GH3/B6. These cells respond to pressure application of T3 (2–5 nl, concentration 1·10−10 M) with an increase in the membrane resistance (Rm) and a hyperpolarization. Spontaneously firing cells become silent.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02126342
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