ISSN:
1573-6881
Keywords:
vacuolar ATPase
;
insects
;
manduca sexta
;
midgut
;
V1V0 dissociation
;
transcriptional vacuolar ATPase
;
insects
;
manduca sexta
;
midgut
;
V1V0 dissociation
;
transcriptional regulation
;
antisense RNA
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Physics
Notes:
Abstract The midgut plasma membrane V-ATPase from larval Manduca sexta,the tobacco hornworm, is the sole energizer of any epithelial ion transportin this tissue and is responsible for the alkalinization of the gut lumen upto a pH of more than 11. This mini-review deals with those topics of researchon this enzyme which may have contributed or are expected to contribute noveland general aspects to the field of V-ATPases. Topics dealt with includenovel subunits or the quaternary structure of the V1 complex, aswell as the regulation of the enzyme's function by reversible dissociation ofthe V1 from the V0 complexes and by genetic control onthe transcriptional and posttranscriptional level.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1005448614450
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