ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation (2014)
    Springer Nature
    Details
    Publication Date: 2014-09-12
    Description: HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation Cell Death and Disease 5, e1414 (September 2014). doi:10.1038/cddis.2014.381 Authors: F De Nicola, V Catena, C Rinaldo, T Bruno, S Iezzi, C Sorino, A Desantis, S Camerini, M Crescenzi, A Floridi, C Passananti, S Soddu & M Fanciulli
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Public health. A sound rationale needed for phase III HIV-1 vaccine trials (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-01-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, Dennis R -- Desrosiers, Ronald C -- Doms, Robert W -- Feinberg, Mark B -- Gallo, Robert C -- Hahn, Beatrice -- Hoxie, James A -- Hunter, Eric -- Korber, Bette -- Landay, Alan -- Lederman, Michael M -- Lieberman, Judy -- McCune, Joseph M -- Moore, John P -- Nathanson, Neal -- Picker, Louis -- Richman, Douglas -- Rinaldo, Charles -- Stevenson, Mario -- Watkins, David I -- Wolinsky, Steven M -- Zack, Jerome A -- New York, N.Y. -- Science. 2004 Jan 16;303(5656):316.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Scripps Research Institute, La Jolla, California, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14726576" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines/*immunology ; *Clinical Trials, Phase III as Topic/economics ; Costs and Cost Analysis ; HIV Envelope Protein gp120/*immunology ; HIV Infections/*immunology/prevention & control/therapy ; HIV-1/*immunology ; Humans ; Immunization Schedule ; Immunization, Secondary ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Helper-Inducer/immunology ; Thailand ; United States ; Vaccines, Synthetic/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-09-27
    Description: The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4(+) T lymphocytes for certain strains of human immunodeficiency virus-type 1 (HIV-1). The CKR5 structural gene was mapped to human chromosome 3p21, and a 32-base pair deletion allele (CKR5Delta32) was identified that is present at a frequency of approximately0.10 in the Caucasian population of the United States. An examination of 1955 patients included among six well-characterized acquired immunodeficiency syndrome (AIDS) cohort studies revealed that 17 deletion homozygotes occurred exclusively among 612 exposed HIV-1 antibody-negative individuals (2.8 percent) and not at all in 1343 HIV-1-infected individuals. The frequency of CKR5 deletion heterozygotes was significantly elevated in groups of individuals that had survived HIV-1 infection for more than 10 years, and, in some risk groups, twice as frequent as their occurrence in rapid progressors to AIDS. Survival analysis clearly shows that disease progression is slower in CKR5 deletion heterozygotes than in individuals homozygous for the normal CKR5 gene. The CKR5Delta32 deletion may act as a recessive restriction gene against HIV-1 infection and may exert a dominant phenotype of delaying progression to AIDS among infected individuals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dean, M -- Carrington, M -- Winkler, C -- Huttley, G A -- Smith, M W -- Allikmets, R -- Goedert, J J -- Buchbinder, S P -- Vittinghoff, E -- Gomperts, E -- Donfield, S -- Vlahov, D -- Kaslow, R -- Saah, A -- Rinaldo, C -- Detels, R -- O'Brien, S J -- DA04334/DA/NIDA NIH HHS/ -- MO1-RR06020/RR/NCRR NIH HHS/ -- N01-HD-4-3200/HD/NICHD NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1996 Sep 27;273(5283):1856-62.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Genomic Diversity, National Cancer Institute (NCI), Frederick, MD 21702-1201, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8791590" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*genetics/immunology/physiopathology/virology ; Base Sequence ; Chromosome Mapping ; Chromosomes, Human, Pair 3 ; Cohort Studies ; Disease Progression ; Genes ; HIV Infections/*genetics/immunology/physiopathology/virology ; *Hiv-1 ; Hemophilia A/complications ; Heterozygote ; Homosexuality, Male ; Homozygote ; Humans ; Immunity, Innate/genetics ; Male ; Molecular Sequence Data ; Receptors, CCR5 ; Receptors, Cytokine/*genetics ; Receptors, HIV/*genetics ; Risk Factors ; *Sequence Deletion ; Survival Analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    Electronic Resource
    Electronic Resource
    A family of co-robotic surgical set-ups (2003)
    Bradford : Emerald
    Industrial robot 30 (2003), S. 564-574 
    Details
    ISSN: 0143-991X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The paper describes co-robotic devices, aiming at accomplishing surgical operations by remote overseeing and manipulation. The concept design of a modular layout is presented, assuring body penetration by curved and twisted paths, with minimal impact. The fixture develops as an articulated snake-like forearm, carrying a wrist and the pertinent effectors; scalpels, scissors, sewing rigs, cameras, etc. The fixture is a good example of a micro electro mechanical system, with force-actuation and shape-control being intrinsic properties. Different options are studied and the related basic operational characteristics are summarised and compared. The jointed forearm might include one to six blocks. Specifically, task-oriented end-effectors are considered, e.g. a self-operating sewing rig, able to operate with a single thread. The robot co-operation will drastically modify surgery practice, giving freedom from anthropocentric bounds; the paper introduces such opportunities, with comments on typical control strategies and hints on actual performance, inferred by testing on virtual reality and digital mock-ups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/01439910310506837
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Gecko, the walls cleaner (2002)
    Bradford : Emerald
    Industrial robot 29 (2002), S. 538-543 
    Details
    ISSN: 0143-991X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The paper discusses commercial cleaning robots available on the market. It introduces Gecko, a virtual prototype of a cleaning robot. Gecko has been conceived, assembling mainly standard components, and the actual behaviour in running conditions is shown by using consistent digital mock ups: Gecko is able to fully clean and sanitise floors, walls and ceilings. To comply with health needs, the robot cleans surfaces using steam. Details on abilities and components are provided. The wall sustentation is guaranteed by four suction cups. The path planning allows a 2D Cartesian motion. To simplify the robot control, innovative "automatic suspensions" are integrated in the sustain and actuation system. Finally, other possible applications fields for such a robot are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/01439910210440246
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection (1996)
    [s.l.] : Nature Publishing Group
    Nature medicine 2 (1996), S. 405-411 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and serologic techniques were used to identify products of HLA class I, class II and transporter (TAP) genes (also part of the MHC) in homosexual seroconverters to human ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm0496-405
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Optimum geometrical design of multipad externally pressurized journal bearings (1968)
    Springer
    Meccanica 3 (1968), S. 231-241 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary A geometrical characterisation for externally pressurized journal bearings having been defined, the relationship between geometry and dynamic behaviour is investigated systematically in the present paper. The result of the investigation is a set of diagrams covering cases of practical interest not presented to such an extent before.
    Notes: Sommario Dopo aver definito un procedimento per la caratterizzazione geometrica delle coppie rotoidali a pozzetti larghi e profondi, la presente nota fornisce in forma diagrammata l'influenza delle scelte dimensionali sul comportamento dinamico del cuscinetto. I risultati presentati sono originali e di pratico interesse anche in ragione del carattere di sistematicità con cui sono esposti. Lo studio fa riferimento alle deduzioni teoriche sviluppate in tale campo presso l'Istituto di Meccanica Applicata alle Macchine dell'Università di Genova e si inquadra in una organica indagine ivi condotta sulle coppie rotoidali portanti pressurizzate dall'esterno.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02186942
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Experimental study of the behaviour of externally pressurized journal bearings (1973)
    Springer
    Meccanica 8 (1973), S. 129-138 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary Over the past few years many mathematical models have been proposed for the analysis of externally pressurized bearings. But the gaps between experimental observations and the results of model analysis are still wide. These gaps are due to the simplifying hypothesis, that underlie the methods. A mathematical model for designing bearings that takes account of the effects of journal rotation has recently been devised at the Institute of Applied Mechanics of Genoa University. A test stand has also been designed and built, fitted with up-to-date instruments for the experimental analysis of bearings for several journal rotation speeds or for different load conditions. This paper presents a summary of the big program of experimental tests conducted with Italian CNR support and compares these experimental results with the theoretical results obtained by recasting the mathematical model to allow for the principal effects evidenced by the tests.
    Notes: Sommario Negli ultimi anni sono stati proposti molti modelli matematici atti all'analisi dei cuscinetti pressurizzati dall'esterno. Tuttavia nella letteratura si notano ancora notevoli discordanze fra le osservazioni sperimentali ed i risultati dell'analisi su modello. Tali differenze sono imputabili alle ipotesi semplificative adottate nell'impostazione dei metodi proposti. Presso l'Istituto di Meccanica Applicata di Genova è stato elaborato, negli anni scorsi, un modello matematico per la progettazione dei cuscinetti che tiene conto anche degli effetti dovuti alla rotazione del perno. E stato inoltre progettato e costruito un hanco di prova, dotato di moderne strumentazioni atte all'analisi sperimentale dei cuscinetti per varie velocità di rotazione del perno o per diverse condizioni di carcio. Il presente articolo presenta la sintesi del vasto programma di prove sperimentali condotte con il finanziamento del C.N.R. e confronta tali risultati sperimentali con quelli teorici ottenuti rielaborando il modello matematico per tener conto dei principali effetti messi in evidenza dalle prove.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02155855
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Synthetic interpretation of attitude dynamics of a spinning satellite under continuous and pulsed torques (1967)
    Springer
    Meccanica 2 (1967), S. 256-262 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary The problem of the dynamics of a rigid satellite in the case of no damping has been thoroughly treated in several papers[1]; less literature is available on the problem of damped satellites. Furthermore, the formulas describing the dynamics are quite complicated and so their interpretation is not straightforward. This study presents the results of one attempt to interpret the dynamics on the basis of relatively simple physical and cinematic considerations, which lend themselves to an easy interpretation of the performance and a simple determination of the most critical cases, for continuous and pulsed external torques both in the damped and undamped cases.
    Notes: Sommario Il problema della dinamica di un satellite rigido è stato trattato a fondo in vari articoli[1] in assenza di smorzamento. Esistono pochi articoli viceversa sul problema di satellite smorzato. Le formule che ne descrivono la dinamica sono assai complicate e di conseguenza la loro interpretazione non è immediata. Questo studio presenta i risultati di un tentativo di interpretazione della dinamica basato su considerazioni fisiche e cinematiche particolarmente semplici, che si prestano ad una facile interpretazione del funzionamento e a una chiara rappresentazione dei casi più critici sia in corrispondenza di eccitazione esterna a coppia costante che impulsiva.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02153081
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    The Caenorhabditis elegansRAD51 homolog is transcribed into two alternative mRNAs potentially encoding proteins of different sizes (1998)
    Springer
    Molecular genetics and genomics 260 (1998), S. 289-294 
    Details
    ISSN: 1617-4623
    Keywords: Key words RAD51 ; DMC1 ; Homologous recombination ; Trans-splicing ; Caenorhabditis elegans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In prokaryotes, the RecA protein plays a pivotal role in homologous recombination, catalyzing the transfer of a single DNA strand into an homologous molecule. Structural homologs of the bacterial RecA protein, called Rad51, have been found in different eukaryotes (from yeast to man), suggesting a certain level of conservation in recombination pathways among living organisms. We have cloned the homolog of RAD51 in Caenorhabditis elegans. The CeRAD51 gene is transcribed into two alternative mRNAs and potentially codes for two proteins of 395 and 357 amino acids in length, respectively. We discuss the evolutionary implications of these findings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004380050897
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...