ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The tautomerism of the nucleic acid bases cytosine and adenine and some of their derivatives is investigated by means of semiempirical MO methods. The influence of the solvent is estimated using various versions of the reaction field model. In the cases under investigation here, the medium influence does not favour “rare” tautomeric forms having other coding properties in DNA replication process than the “normal” nucleic acid base tautomers. Thus, the probability of their participation in spontaneous mutations seems to be very low.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19843260309
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